Nearly 70,000 people in the United States will be diagnosed with uterine (endometrial) cancer this year. Uterine (endometrial) cancer is the fourth most common cancer in the United States, and while it most often occurs after menopause, it can also affect younger women.

Getting this diagnosis can feel all-consuming. Preparing questions in advance can help you organize your thoughts and have more productive conversations with your doctor to feel more confident in your decisions.

You might consider asking:

• What stage and grade is my cancer, and what does that mean for my prognosis?
• Will I need surgery, and what are the risks and recovery expectations?
• Do I need radiation or chemotherapy after surgery?
• Is hormone therapy a possible option for me?
• How can biomarker testing guide treatment decisions?
• How will treatment affect my hormones or fertility?
• What are the potential short-term and long-term side effects of treatment?
• How often will I need follow-up visits or scans?
• Should I consider joining a clinical trial?
• What lifestyle changes can help support my health during and after treatment?

Surgery is the preferred treatment for uterine (endometrial) cancer, often involving the removal of the uterus (hysterectomy). Your doctor may also discuss removing the ovaries and fallopian tubes, depending on your age and diagnosis. Some patients may need additional therapies such as radiation, chemotherapy, or hormone treatment to lower the risk of recurrence.

Biomarker testing is especially important in uterine (endometrial) cancer. For instance, testing for mismatch repair deficiency or Lynch syndrome can influence both your treatment plan and your family’s health considerations. Knowing whether you should have these tests done early on is an important step.

If you are pre-menopausal or wish to preserve fertility, talk with your doctor about what options may be available. Some women may be eligible for treatments that allow fertility preservation, though this depends on the stage and grade of the cancer.

Supportive services can also make a big difference. Many cancer centers have fertility specialists, nutrition experts, or palliative care teams who can help you manage symptoms and side effects. Social workers or patient navigators may also be available to guide you through insurance and financial concerns. Asking what resources are offered ensures you get holistic care, not just for the cancer itself, but for your overall well-being.

As with many cancers, follow-up care is essential. Uterine (endometrial) cancer can sometimes return, so it’s important to know what signs to look for and how often you’ll need check-ups.

Taking the time to ask these questions will help you better understand your diagnosis and treatment. Bringing a support person to your appointments and writing down answers can make it easier to process the information. Your care team is there to provide guidance, and no question is too small.

You’re not alone. Join the Outcomes4Me Community for a safe space to share your story and connect with others who share your diagnosis.