Swollen Ankles and Bone Pain After Zometa Infusion: Anyone Else?

I would talk to your doctor. Do you have high blood pressure? My blood pressure changed after diagnosis. Also, make sure you drink at least 64 oz of water daily. AIs can cause dehydration and kidney issues.

I have been on Tamoxifen for 5 years. Have had swollen ankles and feet ever since. At first i could not wear my shoes. Its a little better now. I can wear my shoes, but cannot zip anything all the way. I refuse to buy bigger size’s. I am going to get off this poison some day. Taking black seed oil and soursop oil along with it. I see oncologist next month. Im going off i have been on it 5 years now. I would like to feel normal again.

I am having bone loss bone pain muscle pain nausea hot flashes and insomnia, I’ve told my oncologist and he put me on a anti inflammatory drug which hasn’t helped, my primary care doctor keeps sending for his records and they haven’t sent and make excuses for not sending them it’s frustrating and I just want help

What you're experiencing sounds concerning and definitely warrants a conversation with your medical team. While some patients do report various side effects after infusions, sudden swelling with pitting edema and new bone pain should be evaluated promptly by your healthcare provider. Many others in this community have navigated similar questions about treatment side effects, so hopefully others will share their experiences with you as well.