CommunitiesHR+ HER2-Here's a simple title for the given text: Should I Start Radiation Without My Oncotype DX Score?

Here's a simple title for the given text: Should I Start Radiation Without My O...

RC

Community Member

a year ago

Hello fellow BC Warriors!! I am 55 years old and was diagnosed with HR+/HER2- Invasive Lobular Carcinoma in September. I’ve had two lumpectomy surgeries to include 5 lymph nodes. Cancer is stage 1 and lymph nodes were clear. I am post menopause. I am scheduled to start radiation treatments tomorrow but due to an error at my oncologist’s office, we do not have my Oncotype DX results. Initially, he wanted me to hold off on treatment until we received this score but now, he wants me to proceed without it. I’m confused by this sudden change. I know he’s experienced in this field but I can’t help but to be reluctant to begin radiation without knowing what my score is. Also, because the cancer was in my left breast (about 10 o’clock), I am concerned about the long termaffects of this treatment to my heart. Am I being overly dramatic by wanting a cardiologist to also monitor me during and after treatment? Do any of you have any thoughts or advice you could provide me? Thank you!!!!

2
13 comments
Comment
accepted answer

Accepted Answer

This sounds like a challenging situation with the timing mix-up on your test results. Many patients in this community have faced similar decisions about treatment timing and have found it helpful to ask their oncologist specific questions about why the recommendation changed and what factors influenced that decision. Regarding heart monitoring during left-sided radiation, advocating for your cardiac health is completely reasonable - many patients work with their care team to establish appropriate monitoring protocols. The community here has lots of experience navigating these treatment decisions and balancing different concerns, so hopefully others will share their perspectives too.

3+ patients found this helpful

MR

Community Member

a year ago

I personally don’t understand the urgency of having radiation before the oncotype results. How long will it take to get it back? Why radiation and not chemo? You are stage 1 with no lymph node involvement. I think checking with the cardiologist is a good idea, even now or if you wait for the oncotype results. Good luck

1
CS

Community Member

a year ago

I am in a clinical trial DEBRA. Left Invasive lobular cancer, neg nodes, Oncotype 16, tumor 17 mm. The trial omits radiation and only aromatase inhibitors for 5 yrs in one group and radiation and aromatase inhibitors in other group. If oncotype is low then chemo shown in studies not to be beneficial. Ask more questions for sure.

2
JU

Community Member

a year ago

Hi Rhonda. My tumor was on the left also. I waited 3 months between surgery and radiation. They take a lot of measurements to make sure the rad isn’t going to hit what it’s not supposed to. They will likely test you while holding a big breath and without. Sometimes holding the inhale moves your heart further out of the way. In my case, it was better not to hold my breath. Best wishes!

3
SS

Community Member

a year ago

I go for the measurements appointment tomorrow. I’m very anxious about my heart and lungs.

1
JU

Community Member

a year ago

Sylvia you can look at the “target field” after they take the measurements and ask more questions. I was on the fence about it. Since I didn’t do chemo I went with the radiation. I had a large tumor, 5 cm and grade 3.

1
TL

Community Member

a year ago

I had to have an EKG and a stress test before my 30 rounds of radiation. I have the same concerns for heart and lung. My cancer was left breast at about 10:00 o’clock as well. They told me the breath holds help to protect your heart. I guess it’s a wait and see kind of thing.

1
SS

Community Member

a year ago

I’m holding thumbs. 🤞

TF

Community Member

a year ago

I had ductal cell in my left breast. I had a lumpectomy to include to lymph nodes. I did 20 rounds of radiation first and then I got my uncle type back after the radiation. They were all surprised to find it was 27. So then I had TC chemo four rounds, every 3 weeks. I just finished 2 weeks ago. I think it's fine to do radiation before chemo. I wasn't even aware I was going to have to have chemo. I've had some heart issues in 2018 so I was cleared by a cardiologist to have my lumpectomy but I just follow him every 6 months or so. There was no mention of anything radiation or chemo would do to my heart. I don't think that's a big concern in oncology unless you have some heart history or something like that. I have a hard history and they didn't seem very concerned about it. I'm also stage one and lymph nodes were clear.

2
SS

Community Member

a year ago

Thanks, Tammi. I haven’t done the onco test. My oncologist said it wasn’t really necessary if I wasn’t going to have chemo. I’m still curious to know what my number would be though.

1
TF

Community Member

a year ago

It was the deciding factor for chemo for me. If it had been low, I would not have benefited from it.

2
RC

Community Member

a year ago

Sylvia I think it’s still important for you to know that number and understand the recurrence rate. You have to advocate for yourself. Personally, I would ask that they do the test. It can also provide a little peace of mind as well.

1
DT

Community Member

10 months ago

Sylvia, I agree with Rhonda C. They can do the Oncotype test from biopsy/pathology taken at surgery. You should know and it takes almost 3 weeks to get test back. Recurrence rate is of importance too.

CA

Community Member

6 months ago

This sounds like a challenging situation with the timing mix-up on your test results. Many patients in this community have faced similar decisions about treatment timing and have found it helpful to ask their oncologist specific questions about why the recommendation changed and what factors influenced that decision. Regarding heart monitoring during left-sided radiation, advocating for your cardiac health is completely reasonable - many patients work with their care team to establish appropriate monitoring protocols. The community here has lots of experience navigating these treatment decisions and balancing different concerns, so hopefully others will share their perspectives too.

Outcomes4Me

© 2026 Outcomes4Me Inc. All rights reserved.