Has anyone had Zometa injections after breast cancer treatment?

Zometa injections are commonly used as part of breast cancer treatment plans, and many community members have experience with this medication. The treatment can be an important part of managing bone health, and it's natural to have questions about what to expect. Others here may be able to share their experiences and insights about this medication, which could help provide perspective on the treatment process.

I just had zometa as an infusion yesterday and 24 hrs later I’m sick- flu like symptoms and body aches an head pressure. I hope it’s not like this every month. I’m in active treatment though

Some people do experience the symptoms every time. Claritin can help. One rare side effect is osteonecrosis of the jaw. I developed this after nine infusions. Make sure you see a dentist on a routine basis to avoid cavities which can lead to more invasive treatment which can cause the necrosis

Wow really every time can actually happen??! Honestly if it’s just the flu symptoms I’d be ok but the head pressure oh no that was so debilitating. I was taking xgeva and did great with it but because I moved to new state the Medicaid here won’t approve it - I wish there was a better alternative. Thanks for the recommendation for the Claritin I will definitely try that next time

I have had 2 zometa injections so far. I am doing everything 3 months for 2 years. I was told the fly like symposium only present after the first injection. But I had it after both.

Thanks for the feedback.

I have been getting monthly Zometa infusions since April 2025. Also, on oral Letrozole and Ibrance. After an infusion, I’m a little tired but feel fine.

I too was a little more fatigued than usual. I’m on letrozole and ribociclib after surgery and radiation.