CommunitiesBreast CancerWhy would oncologist recommend chemo with low Ki-67 and Oncotype score of 3?

Why would oncologist recommend chemo with low Ki-67 and Oncotype score of 3?

HW

Community Member

4 months ago

Hello everyone. I’m 53. I have invasive lobular cancer with 2 positive nodes. Er+ pr + her 2- . Also premenopausal .Had a biopsy and it said ki-67 was 5%. Then I had a lump back to me with four lymph nodes removed. Ki-67% was 20% grade 2. Margins were not player my tumor was 8.5.. So I opted for a double mastectomy. Surgery went good. Ki-67 was 5% grade1 . It was amended from the lumpectomy. Also, I had a.Onco score which was taken from the lumpectomy which had the higher KI- 67. It was only a 3 . The oncologist still wants to do 16 rounds of chemo six weeks of radiation and hormone therapy for 7- 10 years. She’s going off the score of 20 which was amended to five. Why would I want to take chemo if it’s not gonna do any good? I also have PCOS and I mentioned having my ovaries removed to help with estrogen production. She didn’t wanna hear it and she said it would not affect. Treatment has anybody ever had this happen?

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accepted answer

Accepted Answer

Oncologists consider many factors beyond individual test scores when recommending treatment, including tumor size, lymph node involvement, and overall risk assessment for your specific situation. The discrepancy between different Ki-67 results and questions about treatment intensity are understandably confusing and concerning. Getting a second opinion from another oncologist might help clarify the reasoning behind these recommendations and give you more confidence in your treatment decisions. Many people in this community have navigated similar complex treatment recommendations and found it helpful to advocate for clear explanations of how each factor influences their care plan.

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LH

Community Member

4 months ago

Your choice is your own. I was dx 2023 with invasive lobular in my other breast had double mastectomy and hormone therapy. By 2024 it had metastisized to my liver and spine. Started chemo and am holding it at bay. In some cases chemo cures in others it can add time until your ready to go.

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HW

Community Member

4 months ago

Did you have a low onco score?

WL

Community Member

4 months ago

Hi Hope. Is the oncologist basing it on onco score or based on lymph nodes? Might be worthwhile getting a second opinion from a cancer center too.

MA

Community Member

4 months ago

I’m getting all confused by all of these messages. I too had micro Matises in one lymph node. The lymph node was taken out the same time as the lumpectomy. I’m not sure which sample went to pathology for the onco score. My score was 14 which said I did not need chemo. I’m 68 years old. I think I’m in a different category than a younger woman in her 50s. But I’m not sure If I understand why it matters where the sample comes from as far as the Onco score my breast dr just told me that a sample was going to lab for it, but she didn’t say where the sample came from

LH

Community Member

4 months ago

My onco score was 24 so chemo wasn't started until it metastisized.

HW

Community Member

4 months ago

Saw the doctor again and we are doing chemo because of the tumor size and it was in the lymph nodes. All my scores were great but were this cancer is tricky. They can’t guarantee that it didn’t get the blood spray even though my Onco score was a three. I have to do six weeks of radiation also. And 10 years of hormone therapy.

CA

Community Member

4 months ago

Oncologists consider many factors beyond individual test scores when recommending treatment, including tumor size, lymph node involvement, and overall risk assessment for your specific situation. The discrepancy between different Ki-67 results and questions about treatment intensity are understandably confusing and concerning. Getting a second opinion from another oncologist might help clarify the reasoning behind these recommendations and give you more confidence in your treatment decisions. Many people in this community have navigated similar complex treatment recommendations and found it helpful to advocate for clear explanations of how each factor influences their care plan.

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