What Side Effects Did You Experience with Aromatase Inhibitors?

I have been 9n letrozole for 2 years. I have hot flashes, vaginal dryness, slight hair thinning and just started having finger joint pain but that could be arthritis. I did yard work forv2 weeks which is when that started. Taking it easy now to see if it will go away. Overall not much to complain about.

I had brain fog.

I take Arimidex (Anastrozole). Everyone has different side effects. With me I have a lot of bone aches. Try to stick to one of the meds as long as you can. I have Her 2 triple positive breast cancer. Supposedly it’s suppose to keep the cancer under control. Try to keep positive and eat healthy and try to move around as much as possible. Laying around makes everything worse.

Been on it for 2yrs. Joint and muscle pain, sometimes unbearable and brain fog. But if it keeps the cancer away, I can deal with it.

I've taken Anastrozole for 55 days. The main side effects are hot flashes and joint pain in my knees. I take calcium/vitamin D and osteo biflex supplements, which helps with the joint pain. While the hot flashes can be frustrating, they have been mainly tolerable.

Been on Letrozole approx 6mths. Tumor is residing. Had hot flashes the first week only. No adverse effects thus far. However it can be hard on the bones. Choice thus far to be monitored only.

I did alot of research before I started an AI. Almost every symptom is from estrogen deficiency/ menopause. If can be helpful to find a really complete list of estrogen deficiency symptoms so if you are not feeling well when on the medication you can look at that list. Most doctors aren't going to give you a list like that. You have to do things to help your brain,bones and heart when on these meds. I only had 2 mild symptoms when peri menopause but I eventually started bioidentical estrogen every other day because I knew how important it is for a women's heath. I was only on that for 4 years before I had breast cancer. Think of estrogen as your body's lubricant, everything in your body is drying up on AI. So do the things you need to to lubricant your body in other ways inside and out.....hydration/ moisturizer for all parts skin,hair,eyes,ears,vagina. Eat foods that are good for your heart and arteries. Blessings and strenghth to each of you.

Thank you for bringing up this important topic about aromatase inhibitor side effects. Many community members have shared experiences with these medications, and discussing the various effects can help others know what to expect and feel less alone in their treatment journey.