Community Member
3 months agoI have hormone-positive breast cancer that has returned, and I'm postmenopausal. I previously had a lumpectomy and radiation. My oncologist is discussing treatment options including hormone-blocking medications like aromatase inhibitors with CDK4/6 inhibitors, or chemotherapy regimens. I'm trying to learn more about what to expect with these different approaches. I'd love to hear from others who have been in a similar situation and can share their experiences. • If you've had hormone therapy with CDK4/6 inhibitors for recurrent cancer, what was your experience like day to day? • For those who chose between hormone therapy and chemotherapy for recurrence, what factors helped you make that decision?
Community Member
3 months agoThis is such an important decision, and it's wonderful that you're reaching out to connect with others who have walked this path. Many people in this community have faced similar treatment choices for hormone-positive recurrent breast cancer, and their shared experiences can provide valuable insights alongside your medical team's guidance. Both hormone therapy combinations and chemotherapy approaches have different side effect profiles and daily life impacts that community members often discuss openly here.
Community Member
19 days agoI had no choice between CDK4/6 and chemo. My onc said chemo wouldn’t help me, needed hormone therapy. IDC ER+ PR+ HER2-, for the 3rd time. On Letrozole and will start Kisqali in April. I also just learned I have a PIK3CA mutation. I don’t see me being free from medication any time soon. The good thing is that there are 3 AI’s and postmenopausal women can also use Tamoxifen. If one has too many side effects, you have options. Best wishes for you ❤️
New to the community?
Create an account to connect with others navigating cancer.
© 2026 Outcomes4Me Inc. All rights reserved.