CommunitiesHER2+Seeking advice on endocrine therapy options for triple positive breast cancer

Seeking advice on endocrine therapy options for triple positive breast cancer

CA

Community Member

3 years ago

I’m stuck between a rock & a hard place making the decision on whether or not to proceed with endocrine therapy & if I do which route do I go. I’m triple positive (HR, ER, HER2) and with the ER dominance, my oncologist sees it as a no brainer. I’m not on board yet. She’s recommending Tamoxifen for 5 years & from my research being that in premenopausal I asked why she’s not doing ovarian suppression. Her reason is with me being so leery with the therapy in the first place, she wanted to give me the lesser of the two. However, everything I’m seeing says ovarian suppression + AI is best for me. Does anyone have experience in this situation?

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accepted answer

Accepted Answer

Making treatment decisions can feel overwhelming, especially when weighing different therapy options and their potential impacts on quality of life. It sounds like having open conversations with your oncologist about your concerns and the research you've found could help clarify the best path forward for your specific situation. Many community members have navigated similar decisions about endocrine therapy approaches, and their experiences might offer valuable insights as you work through this choice with your medical team.

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JM

Community Member

7 months ago

I’m older than you sweetheart and am so sorry you’re having to go through this at your age. I was past the menopause when I was diagnosed so was put on Arimidex when I started Herceptin. Tamoxifen never came up as an option so can’t speak to any opinion on that but Arimidex hasn’t been so bad. I’m creaky but I think I was creaky before too. ;-) We’re here for you!

DL

Community Member

7 months ago

I'm also triple positive, ER 91-100%. I thought chemo pushed me into menopause last year, but alas, she started to rear her ugly head in June! I fully expect to be on Tamoxifen for 10 years. I take it religously everyday. When I started to get my period, my oncologist asked if my hot flashes were subsiding. I said, yeah, as a matter of fact I haven't had one in a while. She said my ovaries are recovering from chemo and I'm making estrogen again. I said, the tamoxifin is still the right drug? She gave me a confident yes. All that being said, you have to be comfortable and confident with your treatment plan. There is never any harm in getting a second opinion.

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VG

Community Member

7 months ago

I’m triple positive & my doctor put me on ovarian suppression & AI. I get a Zoladex injection at my doctors office every 4 weeks & I take Anastrazole daily. My doctor said if I can’t tolerate this then we will try tamoxifen.

TR

Community Member

7 months ago

Hola

CA

Community Member

2 months ago

Making treatment decisions can feel overwhelming, especially when weighing different therapy options and their potential impacts on quality of life. It sounds like having open conversations with your oncologist about your concerns and the research you've found could help clarify the best path forward for your specific situation. Many community members have navigated similar decisions about endocrine therapy approaches, and their experiences might offer valuable insights as you work through this choice with your medical team.

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