Has anyone with HER2+ breast cancer tried Enhertu treatment?

Thank you for sharing this encouraging news about Enhertu's expanded approvals and for reaching out to connect with others in the HER2+ community. Many patients have found value in discussing their experiences with HER2-targeted treatments, and this kind of peer support can be really meaningful when navigating treatment decisions. Hopefully, others who have experience with Enhertu or similar therapies will share their insights to help build a supportive discussion around these important treatment options.

I have HER2+ MBC. It's been almost 4 years. I'm on my second line of treatment. Have not needed to have Enhertu yet, but it's a future plan, if needed.

I wish this had come out when I originally had stage 2, HER2+ cancer. Then it probably would've not come back. I hate this disease

I agree Georgia I hate this disease!!

I have HER2+MBC, have just had my fourth infusion with a review in the next two weeks. I appreciate the oncologist listening to me after my first infusion as I had a really hard time. He reduced the dose and said the efficacy would still be the same so ever since my infusions have been much easier to manage. I’m keeping my fingers crossed for some reduction in the tumor sizes at my next pet scan.

I’m starting my first infusion next week I am stage 4 metastatic her2 positive IJC as it has gone to my rib and clavicle. I will not be doing THP only Enhertu with P no radiation or surgery of any kind. Has anyone else done this treatment at stage 4?

Sharlotte, I’ve been doing Enertu every 3 weeks since March, for HER+ MBC, and have my first Petscan Tuesday 9th June, results with my oncologist on 15th June. I will let you know how it goes. Meanwhile let me know if you have any further questions.

Jenny B - I’m Her 2 positive. I did 6 rounds of TCHP. I complained a lot about the side effects. My oncologist reduced my chemo dose by 15% for round 3 and 4. I complained some more. He reduced my dose by 30% for rounds 5 and 6. I finished chemo on May 15. Had my breast MRI on May 14 (so the day before my last round of chemo). I had a complete clinical response. No tumor left in my breast or lymph node! I’m having surgery on June 16. Can’t wait to get the negative pathology report! So I say all the time to people starting chemo, speak up. You do not have to suffer with the max dose of chemo. I was worried with the reduction, but it all worked out!

Melissa H, I have stage 2 HER2 positive and getting ready for my 2nd (of 6) TCHP treatment. My tumor is about 1.7 cm and I have have 1 infected lymph node. What was the size of your tumor and how many infected lymph nodes. I want to understand if I might be able to reduce my treatment too like you.

Truc B - my tumor was 2.7 cm and I had 1 infected lymph node! Goodluck! I don’t think I would have made it through all 6 cycles at 100%. It was rough!!

I have HER2 positive stage 2 breast cancer and had a2.7 cm tumor removed. I have had THP neoadjuvant treatment, a lumpectomy, radiation, and am now on Enhertu every 3 weeks at a reduced dose. I am tolerating it well. I’m so pleased it was approved for my situation.

Jenny I look forward to hearing about your Petscan results. I’m praying for you 🍃

Thank you Sharlotte W. My results today have been very encouraging, a reduction of 50% of my tumors, wonderful news.