Has anyone switched from Phesgo to Kadcyla after treatment?

I am on Kadcyla, half way through my 14 cycles. A few minor side effects but in general I am tolerating it very well.

I did Kadcyla and was able to work missing only a few days. I drive a school bus

I had just 1% cancer remaining after TCHP treatments. I had a small sprinkling of cells in a 4mm area, which was removed during my dmx surgery. Usually, I would have been prescribed Kadcyla, but my oncologist didn't want my neuropathy to worsen, so she kept me on phesgo. I'm also on Letrozole for 5 years.

I just had my 1st Kadcyla about week ago after also finishing chemo and surgery. Its def a little rougher than i was anticipating but smooth sailing after what you've already gone though.

I have had both treatments. For me, Kadcyla is much more effective if you have a tumor that needs shrinking. Phesgo is a great medication for maintenance. I did not have major side effects on either of these treatments. I now have no evidence of disease.

Yes, this is just maintenance, which is why I'm more comfortable sticking with Phesgo and radiation with anastrozole.

I did Kadcyla for 17 cycles, every 3 weeks, because I didn’t have taxol first. I had severe chronic fatigue before breast cancer and was able to tolerate the kadcyla. I live alone with my dog and managed. Did radiation about 3 months after starting the kadcyla, too.

Well, it's still chemo. Not as destroying as AC-T ( doxorubicine (Adriamycin) and cyclophosphamide (Procytox) followed by paclitaxel (Taxol). There is fatigue, some pain, you still need to be as carefull. I think that our weaknesses are revealed under these treatments. How this treatment works is when trastuzumab blocs the her2, the dm1 enters the cell, activates and destroy the cells. As for ac-t chemo, it gets in the body and destroys absolutely everything. Tchernobill! It is one of the best treatment for her2+ when pcr wasn't achieved and a better chance of avoiding reccurences. Personally, I went through every treatment that was proposed. Medecin can't explain the her2 mystery, so I decided to put all chances on my side and follow all the available treatments. You always have the final word for your treatment. I can't say Kadcyla is nothing if you had previous treatments. You're still able to fonction normally on this treatment. Get some rest, exercise, eat healthy and you'll get through it, no problem. Sending you Light S.

Making treatment decisions can feel overwhelming, especially when considering a change from what was originally planned. Both Phesgo and Kadcyla are important HER2+ treatments, and many community members have experience with one or both that they might be willing to share. It's great that you're taking time to think through your options and gather different perspectives before your next conversation with your oncologist.