What Chemotherapy Drugs Are Used for HR-Positive, HER2-Negative Breast Cancer?

My first time also, I have hr+/her- stage 2A lobular breast cancer. I am having Neoadjuvant chemotherapy in my case is 4 round of cytoxan and adriamycin them 12 rounds of paclitaxal. Followed by a double mastectomy then radiation.

I’m stage 3 only right breast had mastectomy on 11/10 will start my 4 rounds on the 18th

If you don't mind me asking. What type of breast cancer do you have.

Hr + her - right breast cancer stage 3 is all they told me

Oh, I hope every thing goes well. I was. Supposed to have my 4th treatment on the dec 4th but come down with the flu, so now I have it rescheduled for the 11th....

Oh no how are you doing with the treatments so far?

So far they haven't been to bad... the worst part has been the neulasta shot to boost your white blood cells. I have lost 90 percentof my hair.

I think I’m going to use the clippers on mine the day before i start chemo that way I have control of it not the cancer or the chemo

They haven’t told be about the neulasta shot yet

Yeah that shot was a surprise to me also. It has to be giving about 24 hours after the chemo. That's the positive outlook with your hair. I should probably cut mine the rest of the way off.

I’m hoping that doing it myself gives me some feeling of control

Well I think it does put you in charge.

I am given a patch for Neulasta that goes off 27 hours after my chemo. My oncologist told me to take Claritin for 4 days to help with bone pain. It worked.

Thanks for the advise I appreciate it

I had my chemo port and mastectomy site drained again it’s pretty sore at the port site

I go to the surgeon tomorrow. To find out when he is wanting to do my surgery.

Stage IA, grade 3, ER/PR+, HER2- Taxitere & Cytoxan 4 doses every 3 weeks. Fulphila shot day 2

The shot to boost WBC was worse than the AC Chemotherapy for me. It REALLY wiped me out really bad that I went off it and am now on a 3 week cycle instead of a 2 week.

Hi, I am ER+, PR+, HER2-. I noticed skin changes on the nipple of the breast I had DCIS with lumpectomy & 6 mths chemo & 6 weeks radiation before 20 years ago. My punch biopsy came back metastatic breast cancer. All scans show only in my breasts. My treatment started in November 2023. I am getting Adriamycin (red devil) and Cytoxin every 2 weeks x 4 treatments. Then 27 hrs later, the Neulasta patch on my stomach delivers the meds. I just had my 3rd treatment on 12 Dec. One more scheduled 27 Dec. Then 2 weeks later I will start Taxol for 12 weeks every week. After chemo is finished, I will be scheduled for a double mastectomy around May 2024. I started losing my hair 13 days after my first treatment. I waited to get it shaved after my second treatment. In the meantime go take some new pictures with your husband or family to cherish while you are on this journey. Now that my hair was buzzed, the tiny hairs left stick me when I lie down. Sorry so long; I wish you and everyone the best on this journey. 💗

Thank you for the advise we will take lots of pictures this weekend

Claritin really does help. I was sceptical at first.

Thank you this second round was just much worse I was hoping for something else too

Welcome to this community - dealing with a cancer diagnosis for the first time can feel overwhelming, and it's completely natural to have questions about treatment plans. The chemotherapy drugs mentioned are commonly used for HR-positive, HER2-negative breast cancer, though the specific combination and sequence can vary based on individual factors that only the medical team can determine. Other community members who have experience with similar treatment protocols may be able to share their journeys and offer support during this challenging time.