HR+ HER2-

Should I skip sentinel lymph node biopsy under new guidelines?

Sentinel lymph node biopsy question. Does anyone regret getting the sentinel lymph node biopsy? My current tumor stats are such that they fall under the new deescalation guidelines where I could skip it? Spoke to both my surgeon and radiation oncologist and they are willing to skip but then I would need full breast radiation. Looking for pros and cons

Has anyone been diagnosed with heterogeneous breast cancer?

Has anyone been diagnosed with or heard of heterogeneous breast cancer? I was diagnosed in August of 25 with metastatic breast cancer that has spread to my long bones,spine, sternum, ribs. Labs look good,scans are stable but Ca-27-29are all over the place and higher than they were when first diagnosed. Prior to this I had been cancer free for 17 years! My oncologist wants me to have 2nd bone biopsy on the right side(first was on the left) and it was Er+ he wants to check to see if the right side is Er-. If so then I will start Enertu infusions. Ali’s my HER2 was what is now considered as low. I am confused and scared and all the things that go along with this. And I’m new here. First time actually posting a question. Any insight or help appreciate

Should I take Arimidex after stage 0 breast cancer at 74?

I am 74. Had hysterectomy 22 years ago. Non functioning ovaries. I have not started this med (anastrozole)yet and not sure the benefits outweigh the side affects in my situation. I recently completed surgery and radiation for stage 0 hormone-positive breast cancer. My doctor is considering Arimidex (anastrozole) as part of my ongoing treatment plan. From what I understand, it works by blocking estrogen production after menopause, which may help prevent recurrence since my cancer type can respond to estrogen. I've heard about potential side effects like hot flashes, joint pain, and bone changes. I'd love to connect with others who have been in a similar situation and hear about your experiences. I am seriously considering not taking this medication. Does anyone else feel the same?

Are there alternatives to MRI-guided biopsies for new breast areas found after cancer diagnosis?

MRI cleared left breast and lymph nodes but found 2 other questionable areas in right breast, 1 in same quadrant and 1 in another plus noted 1.3cm already identified malignancy (mammo said it was up to 4mm) MRI guided biopsies recommended. Any other alternative options? Diagnosis RIGHT BREAST, UPPER OUTER CALCS, 9G VACUUM-ASSISTED STEREOTACTIC CORE BIOPSY: INVASIVE LOBULAR CARCINOMA, ESTIMATED HISTOLOGIC GRADE 2-3, INVOLVING MULTIPLE CORES, MEASURING UP TO 4 MM MICROSCOPICALLY. PLEOMORPHIC LOBULAR CARCINOMA IN SITU WITH COMEDONECROSIS, EXTENSIVE. MICROCALCIFICATIONS NOTED BOTH IN TUMOR AND NONTUMOROUS BREAST TISSUE. The final results are MALIGNANT and concordant with imaging. Surgical and oncologic management is recommended. Recommend breast MRI for extent of disease evaluation given lobular phenotype and extremely dense breasts. Estrogen Receptor 99 % POSITIVE STRONG Progesterone Receptor 75 % POSITIVE MODERATE Ki67, proliferation marker 50 % HIGH HER2 by IHC NEGATIVE 0 HER2 test by FISH* pending Genetic testing results pending

Should I choose lumpectomy or mastectomy for stage 3A breast cancer?

I am 50 years old and in February 6 2026 I was diagnosed with invasive stage lllA breast cancer ER+ HER2- with 1 lymph node with metastasis I am going to have a surgery first and then 20 radiations, and then I will wait for the oncotype test result to decide the treatment. My surgeon gave me the option to have a lumpectomy or mastectomy with or without reconstruction and told me that I will need radiation no matter the surgery. I am struggling with my decision any advices? Thank you

What to expect when breast cancer returns and liver is affected?

Grand Rising everyone. Just went to get my education on my new treatment of herceptin, perjeta and taxol. Actually it's not new because when I was first diagnosed in 2020 this was the same treatment I was clean for 3 years. It came back with mestastic breast cancer in 2024. My liver has been compromised. Did 12 infusions of the Enhertu. It was working for 7 months and now my liver has high numbers again. I'm standing in faith. But doubtful. I'm standing in Grace. But really afraid. I stand in strength and all that I am. 🌸

What should I know when choosing DCIS treatment options?

I was recently diagnosed with DCIS (stage 0 breast cancer) that is hormone-positive. My doctor explained that I have several surgical options to consider, including breast-conserving surgery with or without radiation, or mastectomy. Since my cancer is hormone-positive, there may also be endocrine therapy options to help reduce the risk of recurrence. I'm trying to learn more about what to expect as I work with my medical team to decide on the best treatment plan for my situation. I'd love to connect with others who have been through something similar. • If you had DCIS treatment, what factors helped you decide between surgical options? • What do you wish you had known when making treatment decisions for hormone-positive DCIS?

Is Metformin a good alternative to aromatase inhibitors for cancer?

Is anyone taking Metformin instead of aromatase inhibitors?

Should I get chemo for hormone-positive breast cancer with low risk score?

I have hormone-positive, early-stage breast cancer and I'm under 50 with a low gene recurrence score. My oncologist told me that chemotherapy is what she recommends. The research shows it may provide some benefit for younger patients even with low-risk scores, but it's ultimately my decision to make. I'm 48 and my risk score is 25. I'm trying to weigh the potential benefits against the side effects and impact on my life. I'd love to hear from others who have been in a similar position. • If you had hormone-positive, early-stage breast cancer with a low recurrence score, what factors helped you decide about chemotherapy? • What do you wish you had considered or asked about when making this decision?

Has anyone tried DHEA or testosterone for vaginal dryness with ER+ cancer?

I have er+ her2- with a micromet and I want to know if anyone has had any experience with dhea vaginal inserts to help with dryness or testosterone for vaginal dryness. I’ve been reading more about vaginal estrogen and I’m a little confused about it