HR+ HER2-

Should I take Kisqali with Letrozole for invasive breast cancer?

I’ve read several uplifting posts here, really helps. Thank you! I was diagnosed with Invasive breast cancer late in 2024. I had a double mastectomy in December. From all the imaging, the Dr.’s did not believe the cancer had traveled anyplace and was confined to the small tumor. After the surgery, they found out it had gone to 3 of my lymph nodes. I had 20+ sessions of radiation while taking anastrazole, fairly uncomfortable during that time. They switched me to Letrozole, side effects seem less. My ONCO was 4 and I am so confused about what to do?? Ugh I have several Dr.’s that believe Letrozole is all I need, while several others believe I should be taking Kisquali as well. I struggle with side effects from Letrozole and know Kisquali side effects are more severe. Does anyone have advice for me? Thank you in advance😊

What's it like taking anastrozole for breast cancer side effects?

I have stage I hormone-positive breast cancer and recently had surgery. My doctor prescribed Anastrozole (anastrozole) as adjuvant therapy to help reduce the risk of my cancer returning. From what I understand, it works by stopping my body from making estrogen. My doctor mentioned some potential side effects like joint pain, hot flashes, and possible bone changes that they'll monitor with regular bone density checks. I'd love to connect with others who have a similar diagnosis and treatment plan to hear about your experiences. • What has your day-to-day experience been like on anastrozole? • What tips or strategies have helped you manage any side effects you've experienced?

What's it like taking Anastrozole for hormone-positive breast cancer?

I have stage I hormone-positive breast cancer and recently had surgery. My doctor prescribed Anastrozole (anastrozole) as adjuvant therapy to help reduce the risk of my cancer returning. From what I understand, it works by stopping my body from making estrogen. My doctor mentioned some potential side effects like joint pain, hot flashes, and possible bone changes that they'll monitor with regular bone density checks. I'd love to connect with others who have a similar diagnosis and treatment plan to hear about your experiences. • What has your day-to-day experience been like on anastrozole? • What tips or strategies have helped you manage any side effects you've experienced?

Has anyone experienced A1C increases while on Letrozole after breast cancer?

I had a lumpectomy one ago for a HER2-negative, ER/PR-positive breast cancer of 3mm size. I received radiation therapy after the lumpectomy and started Letrozol. No other side effects other that frozen shoulder. My oncologist doesn’t think this is related. My A1C increased from 6.3 to 6.9 in few months and my oncologist suggested me to take Metformin. Any one else had issue with A1C?

Is MRI-guided biopsy needed after breast cancer treatment?

I had a lumpectomy 3.5 years ago for a HER2-negative, ER/PR-positive breast cancer with an Oncotype DX score of 14. I received radiation therapy after the lumpectomy and was initially on tamoxifen; since July 2025, I have been taking anastrozole. On December 5th, I had a breast MRI with the following finding: Linear non-mass enhancement with progressive/plateau kinetics and a rapid initial phase, measuring 7 × 3 × 3 mm, located in the right breast at the 7:00 position, 7 cm from the nipple. The radiologist recommended an MRI-guided biopsy to exclude DCIS. Has anyone had a similar situation? I am very anxious and terrified that this could be cancer again even though the chances are low.

What to expect after red devil, taxol, and radiation treatment?

I had red devil, taxol, and radiation

Does gabapentin help with hot flashes and insomnia from Letrozole?

Ladies - if taking gabapentin how do you feel with this drug and does it really help reduce hot flashes and insomnia? This is something I a truly struggling while on Letrozole.

What has anyone heard about DIM supplements for cancer?

What has anyone heard about DIM

What's it like going from AC chemo to weekly Taxol treatments?

Can someone who had 4 AC then 12 weekly taxol tell me their experience ? Was AC worse? Is Taxol lighter? Help

Can breast cancer spread to the anal area after treatment?

So I was diagnosed in September 2023 went through lumpectomy and lymph node surgery followed by radiation. So now I have a lump next to my anal area and I don't think it is hemorrhoids. Has anyone ever have breast cancer spread to that area? I am so concerned that is what happened. Please let me know if anyone has or had this problem.