HR+ HER2-

Does PROTEXI cancer vaccine work with hormone therapy for breast cancer?

I have Stage III hormone-positive breast cancer and am currently on ribociclib along with other hormone therapies. I just read about an experimental cancer vaccine called PROTEXI that uses our existing COVID-19 immune memory to help fight breast cancer. The research showed promise for breast cancer patients, though it's still in early stages and clinical trials are just beginning. It might be years before this approach becomes available, but it could potentially work alongside existing treatments to help our immune systems better recognize and attack cancer cells. I'd love to connect with others who have similar diagnoses: • Have you heard about or participated in any immunotherapy research for hormone-positive breast cancer? • What has your experience been like combining different treatments for Stage III breast cancer? Link: https://www.news-medical.net/news/20260727/New-cancer-vaccine-harnesses-COVID-19-immune-memory-to-fight-tumors.aspx

News-Medical

New cancer vaccine harnesses COVID-19 immune memory to fight tumors

In a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history – a synchronized mass immune memory generated through SARS-CoV-2 infection and vaccination – into a powerful ally against cancer.

Is anyone taking Verzenio for breast cancer?

Verzenio- anybody on it? I started it a week and a half ago. The first week the side effects were as expected. Like clockwork last Friday I got much worse and by Sunday I had what felt like a bad diverticulitis flare, I had a fever, nausea and extreme lethargy. I stopped taking it and went to the Dr Monday. He told me to stop taking it for now ran a lot of blood tests and ordered a ct scan of my abdomen. Has anyone had a similar experience. I’m afraid to start it again.

Does Afinitor work for metastatic breast cancer?

I am about to start my third line of treatment for metastatic breast cancer. Ibrance worked for 15 months followed by Piqray/Truqap for two years. Truqap has lost its effectiveness, and two options were considered: Afinitor with fulvestrant or Xeloda oral chemo. I opted for Afinitor and would like to hear from others re: side effects, effectiveness, etc. Thanks.

What supportive care options helped you most during breast cancer treatment?

I have metastatic hormone-positive, HER2-negative breast cancer and I'm currently on Kisqali (ribociclib) with hormone therapy. I've been learning about supportive care options that focus on managing symptoms and improving quality of life alongside my treatments. It sounds like these services can help with comfort and daily living throughout the treatment journey. I'd love to hear from others with similar diagnoses about your experiences with supportive care. • What types of supportive care have been most helpful for you during treatment? • What do you wish you had known earlier about supportive care options available to you?

How to manage anxiety during breast cancer treatment?

I'm going through breast cancer treatment and have been experiencing a lot of anxiety lately. I'm currently on Anastrozole (anastrozole) and Letrozole (letrozole), and I know anxiety is pretty common during cancer treatment. Between managing everything that comes with cancer and the hormonal changes from treatment, I'm dealing with feelings of worry and uneasiness that feel overwhelming at times. I'd love to hear from others who've been in similar situations and learn what helped you get through this part of your journey. • How did you manage anxiety during your breast cancer treatment? • What strategies or support helped you feel more at ease day to day?

Why did my period change on tamoxifen?

I’ve been on tamoxifen for a year now. A few months in, my periods went from a 24 day cycle for 4 days, down to a 31 day cycle for 3 days…. I thought it as just going to continue to lessen my period, however this past month it jumped back up to a 24 day cycle for 4 days and heavy and painful. Prior to tamoxifen I always averaged 24 days for 4 days. I’m now worried the tamoxifen isn’t working? Anyone else experience this?

How do I manage pain after bilateral mastectomy as a recovering addict?

I am hr+ her2 - I have a tremendous family history of breast cancer with one maternal Aunt having triple negative and another with mutation of BRCA gene no cancer. My genetic testing came back negative. I have stage 1A. I am highly considering bilateral mastectomy. I do not want radiation whatsoever. I am also a recovering addict, 10 years clean (back disc ruptured ( oxycontin days. I am so afraid of the pain that will be caused from this surgery. I do have a safe plan, recovery at my mom's who will control my medication. Does anyone have any.inout or suggestions?

What does a high ONCO score of 56 mean for cancer treatment?

High Onco Score Hi all. I have an ONCO score of 56, has anyone else experienced this very high score? It freaks me out and hoping for some positive reassurance!

Anyone on Kisqali, Faslodex, and Zometa? Side effects feedback?

Hello everyone, I wanted to ask if anyone is on kisqail ,faslodex injections and zometa I know everybody’s treatment is different. However I would like to know feedback on the medication due to. I will be starting this coming week and would like to know more about it and feedback in regards to side effects how you feel etc. much appreciate it

Has anyone tried antidepressants for low energy and mood during cancer?

Has anyone started an antidepressant because of low energy, low mood, feeling like you’re just on autopilot, and struggling to get out of a funk? If so, what medication did you take, and did it help? Also, who prescribed it for you—your primary care physician, oncologist, or another provider? I’d appreciate hearing about your experience