CommunitiesHR+ HER2-Does gabapentin help with hot flashes and insomnia from Letrozole?

Does gabapentin help with hot flashes and insomnia from Letrozole?

GJ

Community Member

3 months ago

Ladies - if taking gabapentin how do you feel with this drug and does it really help reduce hot flashes and insomnia? This is something I a truly struggling while on Letrozole.

16 comments
Comment
SS

Community Member

3 months ago

I take 400 mg gabapentin in the evening for back related issues and am and anastrazole. I do not feeling like it helps with my hot flashes.

3
CA

Community Member

3 months ago

Managing side effects from hormone therapy like Letrozole can be really challenging, and many community members have shared similar experiences with hot flashes and sleep difficulties. Gabapentin is sometimes prescribed off-label for these symptoms, and hearing from others who've tried it could provide valuable insights for your discussion with your healthcare team. Connecting with fellow community members who understand what you're going through can offer both practical tips and emotional support during this difficult time.

0
VF

Community Member

3 months ago

Gabapentin did nothing for me. I have been struggling terribly with insomnia. I’ve come to dread the end of the day.

5
TS

Community Member

2 months ago

It only works for couple days for me so I doesn’t use it on the regular

1
JG

Community Member

2 months ago

I don’t take it but Veozah is out. Non hormonal med for hot flashes.

1
EC

Community Member

2 months ago

Veozah does work….. but it only last for about 3-4 months.

KC

Community Member

2 months ago

I was taking gabapentin 300 mg and moved to 100 mg and I don’t think it helps me . I stopped it but I do think it was lightening my night hot flashes

SS

Community Member

2 months ago

Vicki I agree. I too dread the end of the day and I am often exhausted. 4 different sleep aids and without them I am up all night.

2
TH

Community Member

2 months ago

What sleep aids are you taking. Nothing has worked for me

1
KC

Community Member

2 months ago

I take magnesium glycinate. I take 800 mg at night. I also take as fast asleep gummy.

1
CQ

Community Member

a month ago

I was prescribed gabapentin 200 mg twice a day for the nerve pain that I got during radiation. At night, I take it with magnesium it still have a very hard time falling asleep

VF

Community Member

a month ago

Ladies, I had to stop endocrine therapy. It was absolutely destroying my quality of life, and I really think the stress, depression and insomnia it caused could lead to a recurrence. I just rely on a targeted therapy, (Lynparza,) and the metabolic diet to stay recurrence free. It’s been several months since I stopped taking any endocrine blockers, got off ALL sleep prescriptions, and am finally sleeping 7-8 hours a night. Thank G-d. I feel human again.

1
DB

Community Member

a month ago

Gabapentin does not help with flashes or sweats. I’m not sure it helps with my foot pain or back pain but I have been on 400 at night for years.

SS

Community Member

a month ago

Vicki. I totally get it. I sleep somewhat ok with sleep aids, sometimes - sometimes not, but it wrecks me the next day. And I have some joint pain. Srsly considering alternatives.

KC

Community Member

3 days ago

Did not help with night sweats or insomnia for me.

PB

Community Member

a day ago

300mg of Gabapentin plus Magnesium enables me to sleep 5 nights out of 7. I was on Letrozole for a year. Starting Exemestane tonight to see if it lessens my joint pain.

Outcomes4Me

© 2026 Outcomes4Me Inc. All rights reserved.