Community Member
a month agoI'm currently on Opdualag immunotherapy. They postponed my last infusion because of inflammation of my core muscles based on my symptoms and bloodwork. HIGH LDH HIGH CRP HIGH CK I'm now on a 5 week course of prednisone. Anyone have this happen? We're you able to resume your IT (immunotherapy) after prednisone? I also have to be followed up by a rheumatologist to come up with a plan so I can resume immunotherapy. Hinting that they might need to add another med to conteract what immunotherapy is doing to my muscles. Anyone out there that might have similar issues like this?
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a month agoHi Donna. I was on opdivo and yervoy. I actually only got 2 doses. Stopped due to Improvement on pet scan it ended up giving my a bad colitis however. Was on 8 weeks of prednisone taper which helped a little. Also got 2 doses of remicade and 1 dose of entyvio for the GI symptoms it has gotten better but not completely normal yet surgery 2 weeks ago showed complete response to the meds however so that was good news!! Will only need every 3 month pet scans for followup now .. good luck to you
Community Member
a month agoMany patients experience muscle inflammation as a side effect of immunotherapy, and treatment teams often use prednisone to help manage this issue. Resuming immunotherapy after addressing inflammation is possible in many cases, though the decision depends on various factors that the medical team and rheumatologist will evaluate together. Connecting with others who have navigated similar challenges with muscle-related side effects during treatment can provide valuable support and insights during this process.
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a month agoHi Donna, I had the same issue but it was my liver counts that shot way up. They put me on a high dose of prednisone for about a month then slowly brought me down to a maintenance dose before taking me off. It took about two months before I could resume my treatments again. I hope they get things worked out for you so you can resume your treatments.
Community Member
a month agoThank you William. I'm glad it was only 2 months. I hope I am as fortunate as you.
Community Member
a month agoMissing treatments is scary but the prednisone seemed to help a lot, hoping itโs effective for you as it was for me. Keep us posted
Community Member
5 days agoHappened to me. On Opdualag. Liver enzymes shot up. Prednisone brought them down. Still on a small dose. Something shot my calcium way up. Got it down. For me it's been a roller-coaster but overall I'm hanging in there. A few more treatments until my next CT Scan. PET scans never lit up. ๐ค Patience is key. ๐๐
Community Member
5 days agoHi David, i recently switched my care to UPMC Hillman cancer center. They put me on Opdivo and Yervoy, the Yervoy is only for the first 4 treatments then just the Opdivo. So far my counts have stayed in check except for my thyroid is all out of whack so on synthroid. I hope you are doing well
Community Member
5 days agoGood to hear from you William. Overall I feel better than I have since last October, when all of this started. My energy level isn't where I'd like it to be but it's improving, slowly. Right after the Opdualag treatment is the hardest. That's coming Wednesday. I wish you the best and pray your treatment goes well. ๐๐๐
Community Member
4 days agoI know the feeling, I always feel wiped out a few days after treatments but like they say we canโt let the bad days win. I am happy to hear you are feeling better. Praying your next scan goes well. I am awaiting my next one as well.
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