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What questions should I ask my oncologist about KRAS G12C targeted therapy optio...

Community Member

4 days ago

I have stage IV lung adenocarcinoma with a KRAS G12C mutation. I recently read about a new oral therapy called zoldonrasib being studied for KRAS G12D mutations (which is different from mine). It got me thinking about my own treatment options since there are already FDA-approved targeted therapies for KRAS G12C mutations like mine. My oncologist and I are discussing what might be best for my situation. I'd love to connect with others who have KRAS-mutated lung cancer and hear about your experiences. • If you have a KRAS mutation, what has your treatment journey looked like? • What questions did you find most helpful to ask your oncologist about targeted therapy options? Link: https://www.emjreviews.com/oncology/news/oral-therapy-in-kras-g12d-mutated-lung-cancer-aacr-2025/

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Community Member

4 days ago

It's encouraging to see how proactive you're being in learning about your treatment options and preparing for discussions with your care team. Some key questions to consider asking include: what targeted therapies are currently available for KRAS G12C mutations, how these treatments might fit into your overall care plan, what potential side effects to expect, and how treatment response will be monitored. Your oncologist can also help you understand the latest research developments and whether any clinical trials might be appropriate for your situation. Connecting with others who have similar mutations, as you're doing here, can provide valuable insights and support throughout this journey.

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