Has anyone had success with Letrozole and Ibrance for metastatic breast cancer?

I was on Ibrance almost 2 years and then it stopped working for me

I have mets to my lung. My last scan showed no evidence of disease. I know women that have been ned for 5 and 6 years. I have been on it for 7 months.

Glenda I have breast cancer metastasized to the lungs what kind of treatment do you have that is NED now. Thanks

Polar B I am on Ibrance and letrozole. I also work out weights and cardio four times a week.

I also have stage 4 to my bones. I was diagnosed in October 2020.I have been on Ibrance and letrozole the whole 3 years. I Have done pretty well with this treatment. Very minimal side effects. Just recently joint pains from the letrozole. I wish you much success and longevity coping with this❤️

I’ve had Stage 4 metastatic for 11 years. Original breast surgery 47 years ago. I was on Letrozole for 9 years when it stopped working. Now on Ibrance and Xgeva. Minor naseau and weakness. Worse thing is the neuropathy . I do use legal medical marijuana for the bone pain (mets to bone, liver and sternum). Doing fairly well, but then I am 73 🙃‼️

Wow, youre situation is giving me new hope.♡ Im newly diagnosed with stage4 breast cancer that met. to liver 6/ '22.

I was on both for almost 2 years. Just started Faslodex shots on Monday & Kisqali yesterday. Had metastasis activity in my clavical.

I was on Ibrance for 34 months before it stopped working now on fulvestrant And ipataserib for 33 months so this month it will be 6 years mbc with bone Mets

Yes,so far. It has been working for me for 3 years now.

Hi Swarna, I had mets in my lungs, and possibly in my ribs too. I started Ibrance & Letrozole in June 2022. On my last CT scan in Sept 2023 there was no visible metastasis, and my side effects on these meds are pretty manageable. I hope you have good results too. ❤️ Be sure to communicate with your doctor or pharmacist if you have any side effects or any questions as you go.

I have mbc metasized to my bones an lung started out on tamoxifen had horrible side effects after 3 big ass needles to drain fluid now take letrozole an that's it other than my crazy meds. So far I've been 6 months off of oxygen and getting my butt outside more hopefully it keeps it up oh yeah I did the ivermectin also maybe it is the "cureall"

I was on IBrance and Letrazole for 2 years it worked, the only reason I had to stop was due to WBC going too low (down to 0.6).

It worked for over two years for me. I also have Mets to my bones.

This is an interesting site. I hope someone takes the info we provide here and uses it to research what meds have been successful.

It's encouraging to hear that your current treatment approach appears to be showing positive results. Many patients in this community have shared experiences with these medications for bone metastases, and connecting with others who understand this journey can provide valuable insights and support. Consider sharing more about your experience when you feel comfortable, as it could help fellow community members who may be considering or currently on similar treatment paths.