Are Kisqali side effects causing muscle loss and body changes?

The side effects you're describing - muscle and fat loss, hair texture changes, blood pressure fluctuations, and sleep difficulties - are concerns that many patients on CDK4/6 inhibitor treatments like Kisqali report experiencing. These physical changes can be distressing, especially when you're doing everything right with diet and exercise. It's encouraging that your test results are stable, and bringing these specific symptoms to your oncology team's attention can help determine the best approach for managing them while continuing your treatment.

I can't take amlodipine. It started dropping my BP too low even on the lowest dose. You should talk to your doc about changing meds. Mine dropped so low, I went to the ER. The other side effects are most likely from the Kisqali. I, too, had so many side effects from Kisqali that I had to stop taking it. There a several CK4/6 to use.

I have been on Kisqali now for 2 years.. first on 600 a day but my body just couldn’t do it.. lost my job cuz I was too tired and couldn’t walk as much as needed.. I am now in 400 hair loss yes… started a while ago I just literally chopped it all off and wear head stuff hoods .. I find myself needing a pain pill as soon as I open my eyes otherwise I am in pain.. joints muscles and I hate it… but on the bright side stg 4 MBC 2 years since the dx… so keep keeping on.. I know my blood pressure goes up and down.. exhausted.. but we are here.. Gods given us another day.. I have no prognosis due to its all through my lymphatic system… so trying to figure why.. but I’m here for you if u need me.. not sure if I’ve answered questions… chemo brain lolol just forgetful and trying lololol