How is Ibrance and Letrozole Treatment Working for You?

I have been on Ibrance and anastrozole since March of 2024. I, too, have stage four mastastic breast cancer in my right lung. I am on oxygen most of the time during the day and continously during the night, for sleep apnea. As for side effects, I have a cough at night and sometimes when I eat. I have coughed all my life due to weak bronchial tubes, so I can't really know if my meds are the reason. Ibrance does list cough as a possible side effect. So far, everything seems to be under control. Take care and God bless.

Thanks for sharing your story Shirley. So far I have developed mouth sores, diarrhea and severe depression. I don't think it helps that I lost my mother 6 weeks before I was diagnosed with recurring breast cancer that has now spread to my lungs. I have tried to find cancer support groups in my area, but have had no luck.

I’m on Ibrance and Fasledex and Xgevia. Hot flashes unbearable but my doc prescribed oxybutrin (for over active bladder). It has made a BIG difference. My metastatic breast cancer is in my bones and appendix and my omentum.

I’m on Ibrance, Fulvesterant, Zometa, and Itovebi. Had minimal side effects but the Itovebi is giving me some issues (high blood sugar, fatigue). Have only been on it 3 weeks tho. It’s the Metformin for the high blood sugar that’s really annoying (diarrhea) and they just added Jardiance too. My cancer markets are going down though since I started the Ibrance and Fulvesterant. I have MBC to the bones…initial breast cancer was 18 years ago and took Aromasin for 10 years. Thought I was protected but I guess nothing’s foolproof forever.

I was 19 years post original bc 2a. Did chemo too. I have nodules in my lungs and use x oxygen. 3 weeks ibrance with anastrozole.

I just finished 3 weeks but last night got dizzy which may indicate low platelets so Mon going for blood check. I think I may need lower dose.

That was my first line of treatment, too. I had disease progression at about 18 months. Bone lesions to my skull, they were radiated. Switch to Ibrance with fluvestraunt for 5 years. A nice long run. The last 2 years haven't been as successful. I now have new bone, liver, lung lesions. Today I had my first chemo infusion of Taxol, praying it will work. I'm at 9 years 8 months. I prayed for at least 10 years. God is Good 🙏

Starting a new treatment can bring up many questions and emotions, especially when managing metastatic breast cancer. Many community members have shared their experiences with this combination therapy, and connecting with others who understand this journey can provide valuable insights and support. Consider sharing any specific concerns or side effects with the community, as others may have helpful tips for managing treatment alongside their healthcare teams.