What treatment options work for K-ras G13C lung cancer mutation?
Community Member
10 days agoHello, I was diagnosed with lung cancer T2bN2Mx in June 2024. I have K-ras G 13C mutation. I'm finding that to mean there's very few treatment options. Initially I was on carboplatin/pemetrexed/pembrolizumab. I developed a very serious toxic reaction that blistered most of my skin. I'm currently taking docetaxel/ramucirum every 3 weeks indefinately. The side effects are so toxic I can't eat or drink for 7-10 days. There's many other side effects as well. I'm hoping to find anyone else that has the K-ras G 13C mutation and what your treatment plan is. Thank you in advance!
Community Member
9 days agoTreatment options for KRAS G12C mutations have expanded significantly with targeted therapies like sotorasib and adagrasib, but unfortunately KRAS G13C mutations don't currently respond to these same treatments, making this a particularly challenging situation. The severe side effects being experienced are concerning and worth discussing with the oncology team, as there may be supportive care options or alternative treatment approaches that could help manage symptoms while maintaining treatment effectiveness.
New to the community?
Create an account to connect with others navigating cancer.
Related Questions
- Seeking Help for Severe Skin Reactions to Lung Cancer Treatment
- Should I Wait for Clinical Study Results or Start Cancer Treatment Immediately?
- Why isn't my lung cancer tumor shrinking after treatment?
- Facing Lung Cancer: Nervous About Starting Chemotherapy
- How do I talk to family about end-of-life with Pancoast tumor?
- "Stage 3B Lung Cancer: Can I Trust Being Told I'm Cured?"
- How do I find clinical trials for stage 3b NSCLC recurrence?
- What treatment options work for K-ras G13C lung cancer mutation?
© 2025 Outcomes4Me Inc. All rights reserved.