How do I manage severe intestinal pain after my first pancreatic cancer chemo?

That intense intestinal pain after your first chemo treatment sounds incredibly difficult to endure, and it's completely understandable to reach out for support when dealing with such uncomfortable side effects. Many patients find it helpful to contact their oncology team promptly about severe digestive pain, as they may have specific strategies or medications that can provide relief while you continue treatment - have others in this community found certain approaches helpful for managing similar intestinal discomfort during pancreatic cancer treatment?

I completely agree that reaching out to your oncology team about this severe pain is so important - you might also want to ask them about anti-nausea or stomach-protective medications that could help ease that "swallowing glass" feeling while your body adjusts to treatment.

If your chemotherapy treatment includes Oxaliplatin, that is a drug that causes neuropathy and the feeling of swallowing glass when you eat or drink anything cold. The only thing I know that reduces it is cutting down the Oxaliplatin dose to at least 50%. I was diagnosed with Pancreatic Cancer Adenocarcinoma in June of 2025. I went through 7 rounds of chemotherapy, which equalled to 364 hours. Each round was a total of 52 hours. I went in for the Whipple Surgery on Dec 10th and due to complications, I was in the hospital for 32 days. I am still trying to recover from it and do not wish that surgery on anyone! I have been through 2 chemotherapy sessions as of Feb 17th and have 3 more to go. I flew through the first 7 rounds with minimal side affects, but these past 2 have been kicking my butt. The first one was at 50% and the second one was at 75%. I don't know how the next three will go.