How did genomic testing like Decipher influence your prostate cancer treatment c...

Genomic testing like Decipher can provide valuable additional information beyond traditional markers to help guide treatment decisions, and many community members have found it helpful in understanding their cancer's specific characteristics. The questions about treatment options and blood tests for cancer detection are important ones to discuss with your oncology team, as they can explain how genomic testing results might apply to your specific situation and help you weigh the pros and cons of different treatment approaches.

My insurance denied Decipher test. I have very aggressive and high risk prostate cancer with gleason score of 8. I'm too old for surgery and went with radiation with taking orgovitz, abiraterone and prednisone. Doctor recommended this treatment and said I should get another 10 years. I'm 79 now.

My urologist uses Decipher for borderline cases that are candidates for active surveillance v treatment. As a Gleason 9, I was not a candidate for Decipher, though did have genetic testing looking for germline mutations that might guide treatment and inform my children of cancer risk.

I'm 64 with diagnosis of prostate cancer January 2025 after initial pre-op PSA 10.3 Status post-radical prostatectomy with undetectable PSA for almost one year. PSA then became detectable 0.02 and 3 months later PSA was 0.04 My decipher score was 0.97 placing me at extremely high risk. I was diagnosed at stage 3A after the prostatectomy. I'm scheduled for sRT in June. The high decipher score is driving my decision to now proceed with sRT. My concern was achieving urinary incontinence as much as possible and undergoing vacuum-assisted penile rehab in advance of the radiation therapy. We all know radiation can cause worsening of incontinence and ED overtime. Delaying RT and allowing for return of continence is a good choice if possible.