Coping with Hormone Medication Side Effects Before Radiation

Same here. No other significant side effects. Start radiation in a couple of weeks. Haven’t heard anything about b-12.

Best wishes moving forward Kris and John.

I've been ob Orgovyx 5 months, Zytiga 10 weeks. Radiation mid July. At 3 months Orgo, 1 month Zytiga, something flipped! I stopped feeling so fatigued & muscle atrophy stopped. I've been able to exercise more consistently. Don't get me wrong, it's still not great but manageable. Hope this helps encourage you! We'll get through it!

I am thinking about doing hormone and radiation treatment. Hard decision surgery or radiation? Good luck

Us your PC contained on prostate?

What's your psa & Gleason at? Have you had an MRI & PSMA PET scan?

I've been on Orgovyx for 5 months, Zytiga for 2. It has gotten better w time. Not as fatigued or dizzy. More energy than first 3 months. Radiation next week 28 fractions of VMAT. Any similar treatments out there?

Yes MRI and Pet scan and biopsy came back positive my last PSA was 17.23 down from 19.03 just had PSA test done today .

Scott, what do they recommend for protocol?

Hormone therapy and radiation or robotic surgery was the options they gave me

I take Orgovyx. A doctor suggested vitamin D and glucosamine chondroitin. Helps the bones and joints.

I just started Orgovyx just over a month ago. Honestly I haven't noticed ANY side effects so far. Hoping that continues... IDK? When do they typically start to hit?

3 years Lupron concurrent with two Zytiga and 45 days radiation. Napped daily about two weeks after starting radiation. 61/2 years on, PSA <.1. Feeling good. Walking 6 days and lifting weights 3. Age 77. Grateful for all the treatment.

Vitamin D and glucosamine condroitant recommended to me. Helps with joint pain and good for bones supposedly. Good luck.🤞

I’m on Erleada and Lupron injections also what bothers me the most is the “hot flashes” and pi frequency every -1/2 to 2 hours. Any suggestions? Also, are you on a diet? What do you recommend me please?

Jonathan, not to make light (too much), but hot surges weren’t terribly bothersome, especially during Minnesota winters. Pee frequency wasn’t noticeable given my age and gradual slide into this condition. However, getting up at night was a pain. Curtailing liquid after 5 PM helped. These problems mostly resolved after Lupron shots finished, though I swear I have an occasional hot surge even now, 4 years after end of treatment. That said, winter’s coming!😊 Considering the alternative, I’d do it all again.

I've been on Leuprolide for 3 weeks now and go back to the radiologist on the 24th .

Yes I've been very fatigue alot and headaches. But seems not to bad .

I can only speak to what I've done & found during my journey. It seems like far too often Urologists/surgeons do surgery & ROs recommend radiation. I was first diagnosed 10/24 by urologist with "very aggressive prostate cancer spread to lymphs, Gleason 9,8 &7s. Wanted to immediately usher me into hormone shot & radiation asap." 2nd opinion, Gleason 7s, Orgovyx started then Zytiga 10 weeks later. 2nd mri confirmed prostate & lymphs shrunk 65-70%. Radiation VMAT 28 fractions July/August. Last PSA 0.03, originally 11.6. Everything going as planned. Glad I investigated. I found Resistance training helps (Dr. Rob Newton), Moderate Keto Diet (especially cut sugar & starch), some supplements, lymph stretching (Michael Holland), Dr. Geo Prostate Podcast & PCRI.ORG food sources, Positive Attitude has been proven beneficial for all cancer, My #1 is leaning on God & relying on what Jesus did at Post for Our Healing. My Best Tip: Laugh as much as possible & listen to worship music by fav. Artist when you get down (picks me up immediately)!

Despite ADT improving overall survival in appropriately selected patients, it is accompanied with a range of adverse effects, including negative alterations to BMD, structure and strength, lean tissue mass and fat mass, which may contribute to the increased risk of osteoporosis, falls, fractures and cardiometabolic-related events observed in this population group. Although various guidelines exist for men with PCa treated with ADT, there is a need to implement and evaluate the growing body of evidence supporting the use of lifestyle interventions to ameliorate and manage the adverse effects of ADT. Clinicians should consider referring suitable men to practitioners within the allied health profession (for example, exercise physiologists and dieticians) to ensure these men receive the greatest quality of evidence-based care. Our proposed recommendations are outlined in Table 4. Future trials are required to assess both the risk and benefits of adhering to these guidelines and only then may these be fully incorporated into standard practice for men treated with ADT.

Managing hormone medication side effects can be incredibly challenging, especially when dealing with fatigue that affects your daily routine. It's worth discussing any supplement options like B-12 with your oncology team, as they can best advise what might be safe and effective given your specific treatment plan and upcoming radiation.