Has anyone taken Cabometyx for kidney cancer?

I was on Cabo last year. I unfortunately found the side effects overwhelming particularly diarrhea. My onc says I seem to be particularly sensitive to most targeted therapies and their side effects. I would say it’s worth a shot. I’m 60 and decided I’m not ready to stop fighting yet but I came close on Cabo.

78 is young. They told me that some of the trials look so promising that if you can buy some time that cures are right around the corner. AI is supposed to help in curing cancer completely. Diabetes completely. And so many others. If you are alive five years from now, your life expectancy will be 120 years old. That is worth the fight. 78.....42 years left. Now that sure moves me. You are in my prayers.

Yes the biggest problem was diarrhea and cramps but it slowed my progression for about 18 months.

I threw up every morning and every evening for 9 months. From diarrhea to constipation back to diarrhea. They never figured it out but one day, it stopped. I was told that suffering is the payment for progress, and that didn't help. But just doing something kind for someone else each day gave me relief, I believe. A kind word, sharing with someone in need, helping you mate or caretaker with the smallest task was rewarding. I am so sorry for what is upon you. If we change how we look at things then things we see will change. I'm not wise but I have met alot who are. May God bring knowledge to those that treat you and may God give them the wisdom to use that knowledge properly each time they touch you.

I’m almost 77 and in year seven of my treatment for RCC. Have tried Cabo (which is a TKI) but I experienced some growth with it. On Keytruda now using a TKI called in Inlyta. Been on that for almost 2 years and have been stable. Some diarrhea and nausea, but it’s tolerable with Zofran and Lomotil. Inlyta dosage can be adjusted to accommodate side effects. I took 5mg twice a day for 1.3 years but side effects increased so now I take 3mg twice a day for 3 weeks then have a week off. If Inlyta stops working I will switch to another TKI. Lol, I’m just buying in time and waiting for that cure!  Note: there’s more than 1 TKI available so give Cabo a try and if it doesn’t work switch to a different one.

Attached message Pat

Hi Barry. Not able to see attached message. Sorry.

Many community members have shared experiences with Cabometyx, and concerns about side effects are completely understandable, especially when quality of life is such an important consideration. This medication is commonly discussed here, and connecting with others who have firsthand experience could provide valuable insights about managing potential side effects and maintaining daily activities. Consider discussing specific concerns about side effects with the medical team, as they may have strategies to help minimize impact while still providing treatment benefits.