Has anyone tried hormone therapy with low estrogen receptors for breast cancer?

No I didn’t take that with my TNBC. I would get a 2nd opinion.

I had low receptors as well and I only had chemo and radiation. I asked about taking anything else and was told it wouldn't make a difference and the side effects would be worse than the benefit

Thank you - I questioned my surgeons PA as she was an oncology nurse for 20 years prior to being a PA and she said the same thing - also that 2-3 years ago it never even would’ve been offered as the chance of doing any good was slim and the side effects could be worse.

They want me to take that too since I have 5% and because I had cancer 10 yrs ago. It wasn’t triple neg then. Now it is. But said if problems with it, I can stop. I might get 2nd opinion too

I am TNBC with ER at 4% and went through treatment at a NCI designated research facility and they never mentioned endocrine therapy after surgery.

I don’t know if this will help you or not but it helped me. However, you do what you feel in your gut. That’s how we know. Get 2nd opinion if you have a gut feeling. I have TNBC-Stage 3 almost 5.2x5.6x4.5 cm. Became that big within one month. I’m 61, son 36. He went to appt my PCP recommended who told me he was the best of the best and will treat me as a person not a number. I’m in medical field 42 years, I understand. My son looked at me right before our appt and said if you do not feel 100% sure that you can trust your life in this doctor’s hands after he explains treatment plan, we will go to another doctor until you do. We both had 100% trust in him for so many reasons! As a female and mother I have had so many gut feelings good and bad but the achy ones that are lingering and not 100% means check it out until you are 100% feel you are in good hands whatever you have to do. There is something to say about peace of mind. You got this! 🩷💪🏻

I am also low estrogen (10%). I'm being treated as TNBC with keynote-522 protocol (TC-AC with keytruda), surgery, radiation, then more keytruda (immunotherapy) for several months afterward. Hormone therapy has not been recommended for me. I'm being seen at Dana Farber.

My diagnosis TNBC stage 3, I had 12 chemo treatments, then surgery, I chose to have a double mastectomy, no radiation was necessary, 6 keytrada immunotherapy treatments, and anastozole, so far I have had very few side effects. My suggestion is to be very active in your care, ask the hard questions, do your research, I talked to my pharmacist concerning my medications and possible side effects. A support system is a must, stay positive, and surround yourself with positive people. You got this! 🙏

Many patients with borderline hormone receptor levels face similar decisions about endocrine therapy, and it's completely understandable to weigh the potential benefits against possible side effects. This kind of treatment decision often involves discussing the specific details of your pathology report and individual risk factors with your oncology team, as they can help clarify whether the potential benefits outweigh the risks in your particular situation. Others in this community may have navigating similar choices and could share their experiences to help you feel more informed as you discuss this with your doctor.