Has Anyone Tried the Signatera Blood Test?

The Signatera test is a circulating tumor DNA blood test that some oncologists use to monitor for cancer recurrence, particularly in triple-negative breast cancer cases. Many community members have shared their experiences with this test, and it's completely natural to want to hear from others who've been through the same decision-making process about whether to proceed with this monitoring option.

Yes, I have done it 3 times now - before I started chemo, then every 4 weeks after. It shows how much dna from the tumor is in your blood stream and gives the doctors an idea if the chemo is working. I am happy to report that the amount was ZERO on tests 2 and 3! There really isn’t much to the test - it’s just another blood draw that gets sent out to a different lab. When you’re already getting poked on a weekly basis, it’s no sweat!

Kathy, Natera Signatura ctDNA is the upcoming Gold Standard in earliest cancer detection, for known cancer tumors, being acknowledged and recommended over other breast cancer tests such as CA 27 29 that detects MUC 1 proteins that are not as specific to your personal tumor DNA, showing other benign conditions as well. This ctDNA test is said to be highly sensitive and specific, detecting your personal DNA cancer cells months before any metastasis is seen on PET CT scans. I am also getting this blood test at Oncology specified intervals. Best wishes.