CommunitiesUterine (Endometrial) CancerWhat side effects should I expect from Keytruda and Lenvima treatment?

What side effects should I expect from Keytruda and Lenvima treatment?

SU

Community Member

2 days ago

Hi Everyone, I had a radical hysterectomy in December 2024; my surgeon thought she got all the cancer. I was diagnosed with P53 abnormalities. I had one chemo; couldn’t tolerate the nerve pain so it was stopped. Had 5 weeks of external radiation, then 2 weeks of brachytherapy summer of 2025. I thought we were all done… Sadly, in September they found suspicious nodes in my lungs. After 1 CT scan, 2 PET scans, and 2 bronchoscopies and biopsies, they determined the cancer spread to both lungs. I’m supposed to start Keytruda and Lenvima on Friday, March 6th, 2026, and am scared to pieces. I keep reading so many can’t tolerate it. I’ve read about a ton of side effects; what have people experienced? Has anyone been able to tolerate them? Thank you all for any replies!❤️‍🩹

1
3 comments
Comment
JS

Community Member

2 days ago

What stage was your cancer and what! type? Mine was stage 1a grade 1 a endometrial cancer with a small tumor that had stayed within the uterus wall.. hopeful that after a full historectomy that my cancer is gone. I'll have my 6s week check up in April. I wish you the best. Getting started with treatment will be good. It helps the fear factor leading up to it. Not knowing what will happen is hard. My heart is with you

1
SU

Community Member

2 days ago

Thank you so much for your kind words, Jennifer! My uterine cancer was diagnosed as stage 1, 3c. My surgeon really thought it was all contained and had not spread to my ovaries, cervix, fallopian tubes, or any surrounding areas. Like for most of us, the chemo and radiation were to make sure it had not spread. We are devastated, to say the least. We are truly praying for the best. My heart goes out to you, as well. Praying for your healing!!! ❤️‍🩹

1
CA

Community Member

2 days ago

Starting a new treatment can feel overwhelming, especially after everything you've already been through. While side effects can vary greatly from person to person, many patients do find ways to manage them successfully with their care team's support. Consider discussing your specific concerns with your oncologist before Friday - they can share strategies to minimize side effects and help you feel more prepared. This community has members with experience on similar treatment combinations who may share their perspectives, so hopefully you'll hear from others soon about what has worked for them.

1

New to the community?

Create an account to connect with others navigating cancer.

Outcomes4Me

© 2026 Outcomes4Me Inc. All rights reserved.