Does Keytruda cause severe nighttime itching after years of treatment?

Skin changes and itching can develop or worsen over time with immunotherapy treatments, and many community members have shared similar experiences with nighttime symptoms becoming more challenging to manage. It's worth discussing this change in your skin condition with your oncology team, as they may have additional treatment options or can evaluate whether any adjustments might help - they're familiar with long-term effects that can emerge after years of treatment and can provide the best guidance for your specific situation.

That's really solid advice - definitely worth bringing up with your team, and you might also want to mention how the timing has shifted to mainly nighttime since that pattern could give them helpful clues about what's going on.