Community Member
2 years agoHello everyone! I was wondering if anyone has same condition or any comment : 64years old . Tumor size 4cm , grade 3 , stage B1 , lymph node negative . Er 80% positive , pr negative, HER2 negative. ki67 40% Lumpectomy done and now 2nd cycle of chemotherapy. I’m concerned about high grade (3) , progesterone negative and high level of Ki67 . What do you think about possibility of recurrence after treatment?
Accepted Answer
This is understandably a worrying time, and seeking insights from others who may have similar experiences shows great strength. While each person's cancer journey is unique and prognosis depends on many individual factors that only your medical team can fully assess, connecting with others in this community who understand what you're going through can provide valuable emotional support. Many members here have navigated treatment decisions and concerns about recurrence, and their shared experiences might offer comfort and perspective as you continue your treatment journey.
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Community Member
6 months agoHi Kanishka. I'm thinking that is a difficult question for most of us to answer (regarding the medical part of the recurrance). Stage 1B is good though, you got it in the early part. So I'm thinking that is more treatable. And lymph node negative is good too. No spreading there. I think the grade and Ki-67 go together. I don't know for sure but based on my own research for myself I think that means just the proliferation rate. But again, they guy it early so that is good
Community Member
6 months agoAlso from what I've seen and read on others treatment it seems like your on a good path of treatment. Your own education and good communication with your medical treatment team is a good start. I can't imagine what each of us go through. It's confusing. For me I had to do a lot of research and education.
Community Member
6 months agoWhy did you need chemo? Was it oncotype score or the characteristics of cancer?
Community Member
6 months agoCharissa, I think it’s the size of her tumor. Mine was over 4centimeters and I was told I HAD to have chemo before surgery because of the size ..
Community Member
6 months agoAfter chemo, I am guessing you will be prescribed hormone therapy such as tamoxifen or an aromatase inhibitor such as anastrazole, exemestane or letrozole that are well proven to help prevent recurrence. There is a test called the Breast Cancer Index that predicts whether you would benefit from 5 or 10 years of hormone therapy. It is only for ER+ HER2 - like your cancer. Good luck!
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6 months agoRadeen C Thank you. I didn't realize it was only for ER + HER2 -. I wonder if they can do that test before you even start with the medication. I mean like the blood test that tells you whether chemo will be beneficial for you or not. Or if they can do the test a year in, etc. I'm about to start letrozole and am dreading it
Community Member
6 months agoThanks for your texts . Charissa , the oncologist didn’t advise oncotype test . Just started 8rounds of chemotherapy
Community Member
6 months agoI feel like grade 3 and ki67 40% and PR neg all go together. I am assuming chemo is to shrink the tumor before surgery. Let me know if I am wrong. Once the tumor is addressed, I think you will do fine on hormone therapy. My recurrence was pr 2% and my oncologist said pr was not super important. He was happy about it being a high ER +.
Community Member
2 months agoThis is understandably a worrying time, and seeking insights from others who may have similar experiences shows great strength. While each person's cancer journey is unique and prognosis depends on many individual factors that only your medical team can fully assess, connecting with others in this community who understand what you're going through can provide valuable emotional support. Many members here have navigated treatment decisions and concerns about recurrence, and their shared experiences might offer comfort and perspective as you continue your treatment journey.
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