CommunitiesIn Treatment For Breast CancerSeeking Insights on My Breast Cancer Diagnosis and Prognosis

Seeking Insights on My Breast Cancer Diagnosis and Prognosis

KR

Community Member

2 years ago

Hello everyone! I was wondering if anyone has same condition or any comment : 64years old . Tumor size 4cm , grade 3 , stage B1 , lymph node negative . Er 80% positive , pr negative, HER2 negative. ki67 40% Lumpectomy done and now 2nd cycle of chemotherapy. I’m concerned about high grade (3) , progesterone negative and high level of Ki67 . What do you think about possibility of recurrence after treatment?

1
9 comments
Comment
accepted answer

Accepted Answer

This is understandably a worrying time, and seeking insights from others who may have similar experiences shows great strength. While each person's cancer journey is unique and prognosis depends on many individual factors that only your medical team can fully assess, connecting with others in this community who understand what you're going through can provide valuable emotional support. Many members here have navigated treatment decisions and concerns about recurrence, and their shared experiences might offer comfort and perspective as you continue your treatment journey.

3+ patients found this helpful

ME

Community Member

6 months ago

Hi Kanishka. I'm thinking that is a difficult question for most of us to answer (regarding the medical part of the recurrance). Stage 1B is good though, you got it in the early part. So I'm thinking that is more treatable. And lymph node negative is good too. No spreading there. I think the grade and Ki-67 go together. I don't know for sure but based on my own research for myself I think that means just the proliferation rate. But again, they guy it early so that is good

1
ME

Community Member

6 months ago

Also from what I've seen and read on others treatment it seems like your on a good path of treatment. Your own education and good communication with your medical treatment team is a good start. I can't imagine what each of us go through. It's confusing. For me I had to do a lot of research and education.

2
CR

Community Member

6 months ago

Why did you need chemo? Was it oncotype score or the characteristics of cancer?

1
MB

Community Member

6 months ago

Charissa, I think it’s the size of her tumor. Mine was over 4centimeters and I was told I HAD to have chemo before surgery because of the size ..

1
RC

Community Member

6 months ago

After chemo, I am guessing you will be prescribed hormone therapy such as tamoxifen or an aromatase inhibitor such as anastrazole, exemestane or letrozole that are well proven to help prevent recurrence. There is a test called the Breast Cancer Index that predicts whether you would benefit from 5 or 10 years of hormone therapy. It is only for ER+ HER2 - like your cancer. Good luck!

2
ME

Community Member

6 months ago

Radeen C Thank you. I didn't realize it was only for ER + HER2 -. I wonder if they can do that test before you even start with the medication. I mean like the blood test that tells you whether chemo will be beneficial for you or not. Or if they can do the test a year in, etc. I'm about to start letrozole and am dreading it

1
KR

Community Member

6 months ago

Thanks for your texts . Charissa , the oncologist didn’t advise oncotype test . Just started 8rounds of chemotherapy

GD

Community Member

6 months ago

I feel like grade 3 and ki67 40% and PR neg all go together. I am assuming chemo is to shrink the tumor before surgery. Let me know if I am wrong. Once the tumor is addressed, I think you will do fine on hormone therapy. My recurrence was pr 2% and my oncologist said pr was not super important. He was happy about it being a high ER +.

CA

Community Member

2 months ago

This is understandably a worrying time, and seeking insights from others who may have similar experiences shows great strength. While each person's cancer journey is unique and prognosis depends on many individual factors that only your medical team can fully assess, connecting with others in this community who understand what you're going through can provide valuable emotional support. Many members here have navigated treatment decisions and concerns about recurrence, and their shared experiences might offer comfort and perspective as you continue your treatment journey.

Outcomes4Me

© 2025 Outcomes4Me Inc. All rights reserved.