My Experience with Anastrozole and KISQALI Treatment

I took anastrozol for 5 years and a year after I stopped, my cancer returned and had metastasized to my bones

What are they doing for your bones? I was on Anastrazole for 8 years, 3 months later had a recurrence and now found a lesion on my femur. Waiting on a bone biopsy now. Finished 4 months of chemo last month. Mastectomy on hold till bone biopsy is done.

Jeanne, I'm on Kisqali and exemestane and Xgeva. I have MBC. What stage of BC are you?

Karen and Debbie were you on Kisqali? That is the premise of my question. The combo is for post menopausal metastatic breast cancer. Sounds like Anastrozol is problematic for bone mets. Has this been addressed?

I have cancer in my bones, liver, lungs.. stage 4 MBC. I've been on anastrazole for almost 4 years. I had an issue with xgeva, but not the Anastrazole.

After surgery stage 1 B

I am also stage 1B but was not prescribed Kisqali-only anastrozole-Mastectomy neg lymph nodes -

Positive lymph nodes. Luminol B

Thanks for responding-

Never had Kisqali. On Fulvestrant and will be starting Verzenio soon. Just finished 5 days of radiation on my femur.

My endocrinologist allowed no anastrozole or Kisqali. Going in another direction more integrated approach. Big pharma wants you on long term meds beware.

I'm not taking the Aromotase Inhibitors. Not willing to suffer the side effects. I'm 65 yo with ER+/PR-/HER2-, IDC stage 1, grade 3 tumor removed by lumpectomy no lymph node involvement. Onco score was 20. I've had 21 radiation treatments. No pills! My Bone density shows osteopenia. I'm active on a farm. The AI's can lead to osteoporosis! As well as bone and joint pain that can cause inactivity and fatigue. Very disturbing to read the comments regarding cancer reoccurring after completing the years of big pharma various pills!

@Jeanne H I’m currently taking Kisqali with letrozole and the side effects of the Kisqali suck!! I go Tuesday for my first follow up since being on it an plan to tell him I do not like it at all- I feel better when I haven’t taken it vs when I do!! I’m stage 4 met (both breast, both lungs, rt auxiliary lymph nodes,sternum, spine, pelvis and femurs) not to mention the kisqali is very expensive so see if you qualify for the patient assistance program (22k/ month for the pill(s) I take 600mg a day Wish you the best of luck- if ever need someone to talk with reach out ❤️

I opted out. He agreed. No mets currently. Bless your heart. Stay with the course if you can. I’m praying for you now.

Had bil mastectomies 12/23 25 radiation treatments ended 3/5/23, started anastrozole 3/19/24 after 6 months lost sight right eye from macular edema which is a side effect of anastrozole after a month off medication sight regained spoke with oncologist off medication in six months blood work and see what’s next praying es+pr+her2-

They just put me on Anastrozole, after reading all of your medical nightmares (not stories)I really don't want to be on it. I had appendices with a tumor in it, Breast Cancer, double mastectomy, now have Barrett's disease, all in a year. Don't want any more issues.

Thank you all. I respect all decisions. I’m not buying into big pharmaceutical long term drug dependency under false claims. I’m going for quality of life treatment.

Treatment decisions can feel overwhelming, especially when considering combination therapies that seem intensive. Many community members have shared their experiences with various endocrine therapy protocols, and connecting with others who have faced similar choices can provide valuable perspective as you work through this decision with your care team.