Did anyone else get diarrhea from their first letrozole pill?

Digestive side effects like this can happen when starting new medications, and it's completely understandable to have concerns about what you're experiencing. Many patients find it helpful to discuss any new symptoms with their healthcare team, especially in the early days of starting treatment. Others in this community may have similar experiences to share, so hopefully some fellow members will chime in with their perspectives on managing side effects during treatment.

I completely agree that checking with your healthcare team about this is a good idea, and you might also want to ask them if there are any dietary adjustments that could help ease the digestive upset while your body adjusts to the medication.

My oncologist prescribed Letrozole one year following my surgery for Stage 2 breast cancer. I had gone through adjuvant chemo prior to surgery and post-surgery chemo treatment, without radiation. I had been taking multivitamins on a regular basis, without radiation a high concentration of Vitamin C, E and Biotin, to aid in hair regrowth. I had no adverse side effects to Letrozole. I hope your oncologist is able to help you in a timely fashion.