Are Lupron and Casodex killing my sex drive completely?

These medications are known to commonly affect hormone levels and can significantly impact sexual desire and function - this is a very real side effect that many in this community experience. It's completely understandable to feel concerned about these changes, and discussing them with your healthcare team can help you understand what to expect and explore options for managing this side effect during your treatment journey.

I’m taking some of the same things I am ready to go rogue on my treatment and do my own thing

I am on hormone deprivation therapy as well. I am getting Eligard injections. Which they refer to as chemical castration. Pretty brutal terminology. I to have reduced sexual desire. With enough effort and Cialis I can get an erection. However, achieving an orgasm is next to impossible. It has happened twice in the last 18 months. It wasn’t worth the struggle. The orgasm was at best 10 percent the sensation that it was before. Virtually no actual ejaculation. I am told by my doctor that this distinction will decrease with time after the hormone deprivation therapy is over. But since I am 75 Dr said my sexual recovery will be slower than a younger guy and may not happen at all. Prior to prostate cancer diagnosis 18 months ago I was still quite sexually active with my wife. The good news in this for you and me is that all of this will save us from a long slow death from metastatic cancer. I will give up my sex life for that.

I’ll be finishing my 2 years of ADT this NYE! I’m very excited to get my libido back. At the start we used a pump, sex toys, tried cialis and did the trimix injections(🙄). If anyone goes in my top drawer they’ll find quite a collection of tubes, lubes and battery powered devices! You gotta do whatever it takes. I was only 58 when all this started, and my wife only 55. We were very active and still try to get at it, mainly to satisfy her…hence the drawer of toys. I’ve had a few erections appear on their own and while trying to service my wife, one actual full penetration and orgasm! But, I’ve pretty much given up on forcing it. It’s been about 2 1/2 years and I’m looking forward to getting it all back. They say the Lupron and zytiga im on takes a little longer to wear off than the newer Orgavyx, but, I’ll be only 61 in a few weeks and I’m hoping that will help in getting it back sooner.