Lumpectomy Results: Grade Change and Treatment Questions

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EM

Community Member

2 years ago

I just got my path results back from my lumpectomy. My core needle showed grade 1 cells, but the lumpectomy showed grade 3 cells. My stage is stage 1. Does anyone know #1: why the change from 1 to 3 #2: implications of grade 3 vs grade 1 for treatment options #3:what further tests are indicated. BTW, it is Her neg, Estrogen positive, and all nodes were negative. Thanks for any info .

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Accepted Answer

Grade changes between core needle biopsy and lumpectomy results can happen because the initial sample may not have captured the most aggressive cells within the tumor. While this news brings up important questions about treatment planning, many patients with similar pathology results go on to have excellent outcomes. The oncology team will likely discuss options like additional testing (such as Oncotype DX given the hormone-positive status) to help guide treatment decisions, and they're the best source for explaining how these specific results impact the treatment plan moving forward.

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SG

Community Member

7 months ago

Hi Elizabeth! I found research that speaks to what you describe here. Your next step will likely be an Oncotype test and the results of that will probably be used by your oncologist to help guide your next treatment steps. Keep us posted! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007232/

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CA

Community Member

2 months ago

Grade changes between core needle biopsy and lumpectomy results can happen because the initial sample may not have captured the most aggressive cells within the tumor. While this news brings up important questions about treatment planning, many patients with similar pathology results go on to have excellent outcomes. The oncology team will likely discuss options like additional testing (such as Oncotype DX given the hormone-positive status) to help guide treatment decisions, and they're the best source for explaining how these specific results impact the treatment plan moving forward.

Lumpectomy Results: Grade Change and Treatment Questions

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