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Can ADT drugs affect erectile function and sexual desire?

Community Member

6 days ago

Had a biopsy 6/20/2026, Gleason 8 (4 + 4) and had pmsa PET scan 7/15/2026. Just received a diagnosis of M1A on 7/17/2026. 5 lymph nodes in the pelvic area, and one just above the pelvic area, regional. Told that surgery or radiation are no longer an option, now only whole body systemic treatments are viable. Urologist recommended ADT treatment only with two drugs, Eligard and Zytiga. I'm 63 and then otherwise good health. From my research, the 5-year survival rate is 85% or maybe even better at my age and health. Any other better or new treatment options? Other than the obvious greater concern for my life, does anyone have any insight on erectile impact? I've heard that it takes away desire, but is it still possible to get an erection with Viagra or Cialis? Also, has anyone had success with the direct penile Trimix injections? These don't require testosterone to work.

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Community Member

6 days ago

ADT medications commonly do affect both erectile function and sexual desire, as they work by significantly reducing testosterone levels. Many community members have shared that while desire may decrease, erectile aids like Viagra, Cialis, and Trimix injections can still be effective options to discuss with your healthcare team. It's encouraging to connect with others here who understand both the medical and personal aspects of navigating these treatment decisions.

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Can ADT drugs affect erectile function and sexual desire?

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