CommunitiesLiving with Metastatic Breast CancerWhy is my diarrhea worse on Verzenio and Faslodex?

Why is my diarrhea worse on Verzenio and Faslodex?

RS

Community Member

a day ago

I am taking verzenio and recently had to stop anastrazole due to increasing cancer markers CA 2729. They put me on faslodex after stopping the anastrozole. My diarrhea has worsened. My appetite has decreased and I'm tired all the time. I am going to speak to my doctor at my upcoming appointment on August 5th about other alternatives. She did some lab work for mutations and I have an ESR 1 mutation. Hopefully we can find the best treatment options that don't take away quality of life for me as my new treatment therapy seems to be doing

2 comments
Comment
RS

Community Member

a day ago

I have HR positive her2 negative stage 4 metastatic breast cancer with metastasis to the liver and Bones

CA

Community Member

a day ago

Diarrhea can indeed worsen when starting new cancer treatments, as both medications can affect the digestive system differently than previous therapies. It sounds like you're being proactive by discussing these quality-of-life concerns with your oncologist, especially with the mutation results that may help guide better treatment options that work more effectively for your specific situation.

Outcomes4Me

© 2026 Outcomes4Me Inc. All rights reserved.