Is Ibrance gentler than Verzenio for an 80-year-old with MBC?

Both medications can have different side effects for each person, and what works best often depends on individual health factors and how the body responds to treatment. Many community members have shared experiences with both options, and some find one more tolerable than the other. This is definitely a great conversation to have with your oncology team, as they can consider your overall health, current fatigue levels, and treatment goals to help guide the decision that's right for you.

Nancy, welcome to our blog. Ibrance was my first treatment, for seven+ years. My side effects were almost none. I had explosive diarrhea because of constipation. I solved it with more fiber from foods like apples and pears with skins and lots of water (at least 64 oz daily.) Ibrance can cause dehydration. You should probably wear compression sleeves, check with your oncologist. I only had one node removed. I looked healthy, didn't lose my hair. I started Ibrance with letrozole both pills. After 3 years, I had to switch to Ibrance with fluvestrant (shots once a month) for the next 5 years. My cancer mutated, and nothing has worked since then. I had 7 different chemos. The last 2 months, I am taking Truqap (capilvasertib) pills with fluvestrant) and praying it will work. I get scans at the end of June. I know you can do this. If you fill up a 1/2 gallon jug daily; pour water into a glass and drink it and refill you can track your intake. Praying for you.