Non-Small Cell Lung Cancer Clinical Trials

Has anyone used Selpercatinib for RET+ NSCLC?

NSCLC I was diagnosed in January, had surgery in March, completed 30 days radiation and will complete 4 doses of chemo tomorrow. My oncologist wants to include 3 years of Selpercatinib, which is a relatively new RET inhibitor and treats my exact mutation, as a maintenance therapy. Curious if thoughts and results using this treatment?

Does lung surgery pain ever get better after 2 years?

I had a tumor removed by having the bottom lobe of my right lung removed by surgery 2 years ago then done chemo. Still stay in pain does it ever get any better ?

What should I ask my doctor about EGFR-positive lung cancer treatment?

I have stage IV lung adenocarcinoma with an EGFR L858R mutation and haven't started treatment yet. I just read about some promising research from ASCO 2026 discussing new treatment combinations and first-line options for EGFR-positive lung cancer. The article mentions developments in personalized biomarker-driven therapy and new approaches that could be relevant for patients like me who are just beginning their treatment journey. I'd love to connect with others who have a similar diagnosis and hear about your experiences. • What was it like making treatment decisions when you were first diagnosed with EGFR-positive lung cancer? • Are there any questions you wish you had asked your oncology team early on? Link: https://outcomes4me.com/cancer-topic/lung-cancer-research/nsclc-studies-patients-should-be-paying-attention-to-at-asco-2026/

Outcomes4Me

NSCLC studies patients should be paying attention to at ASCO 2026

Discover short summaries of the exciting new non-small cell lung cancer research presented at the 2026 ASCO Annual Meeting.

Has anyone tried the Pfizer PADL1NK 005 clinical trial for lung cancer?

Anyone in Pfizer clinical trial with PADL1NK 005? I had 5 chemos with Keytruda, Carboplatin and taxol, then 27 aditional chemos with Alimta and Keytruda. Cancer turned my world upsidedown in January 2024 when diagnosed with Stage IV NSCLC. I had treatment every 21 days and idled when pet scan this year revealed progresion to C2. Ten sessions of Radiotherapy and kicked off in the Pfizer trial study last week. Praying for strength in this new path.

What to expect after lung cancer surgery: re-resection vs chemo options?

My doctor is discussing next steps after my lung cancer surgery and mentioned two main options: additional surgery (re-resection) to remove any remaining cancer tissue, or drug treatments like chemotherapy or targeted therapy such as Tagrisso (osimertinib) for certain genetic mutations. The choice depends on my surgical results, tumor characteristics, and overall health. I'm trying to understand what to expect with either path and would love to hear from others who faced similar decisions. • If you had re-resection or adjuvant therapy after lung cancer surgery, what was your experience like? • What questions do you wish you had asked your doctor when making this decision?

Does lung cancer treatment cause diarrhea? Looking for tips to manage it

I have non-small cell lung cancer and I'm currently going through treatment. I've been dealing with moderate diarrhea that started recently - this is something new for me. My care team mentioned that digestive changes can happen during cancer treatment, and I'm planning to discuss this with my oncology team. I'd love to connect with others who have experienced similar digestive issues during their lung cancer journey and hear about your experiences. • How did you manage diarrhea during your treatment, and what helped you get through day-to-day activities? • What tips do you wish someone had shared with you when you first experienced digestive changes during treatment?

Are there paid research opportunities for lung cancer patients to share their experiences?

We’re inviting a small group of NSCLC patients to join a professionally moderated virtual focus group focused on patient experiences, decision making, and access to care. Details: • Monday, March 9 • 5:30–8:30 pm ET • Virtual (Zoom) • $300 thank-you for participants who complete the session If you’re interested, please complete this short questionnaire to see if you’re eligible: https://docs.google.com/forms/d/e/1FAIpQLSfTf8dftF7CV3PaXe-Ca47svV7Nzk6oR2FcHYD6D9KlituQ3A/viewform All information is kept confidential. Your voice helps move lung cancer care forward, and we’d be honored to have you participate.

Google Docs

NSCLC Focus Group

Every story has the power to change what comes next. By sharing your experience with NSCLC, you’ll help researchers and clinicians better understand what patients need most and create a future where care feels more personal and effective. If you meet certain stage and treatment criteria, you may be eligible to participate in a virtual focus group. The session will be professionally moderated and conducted over the virtual platform Zoom. It will last approximately 3 hours. If selected to participate, you will receive $300 as a thank you for your time and insights. Please complete the short...

How do you cope with depression during cancer treatment?

I'm going through cancer treatment and have been dealing with severe depression. My oncology team explained that this is very common among cancer patients. There are multiple things that can contribute to depression during this time, including the stress of diagnosis, ongoing treatment demands, certain medications I'm taking like clonazepam and tramadol, and the physical toll of my condition. I'm working with my medical team to get proper mental health support. I'd love to connect with others who have experienced depression during their cancer journey and hear about your experiences. I've had surgery,they remove a quarter of my right lower lung,where there was cancer. Then they found it on my bronchi lymph nodes.. Went through radiation and chemo treatment with stable results. Now going through immunotherapy. It all takes it toll on me. But I keep the faith. • How did you manage depression alongside your cancer treatment? • What kind of mental health support was most helpful for you during this time?

How do you cope when remission isn't possible?

Hi, how you deal with the fact that you will never go into remission?

How do stage IV lung cancer treatment options differ from earlier stages?

I have stage IV lung cancer and came across an article about a study looking at immunotherapy treatments. The research was focused on stage III lung cancer, where patients receive immunotherapy after chemo and radiation for cancer that hasn't spread beyond the chest area. My situation is different since stage IV means the cancer has spread to other parts of the body, so we typically start with different treatment approaches right away rather than the sequence they studied. It got me thinking about how treatment paths can vary so much depending on stage. I'd love to connect with others who have navigated similar decisions. • If you have stage IV lung cancer, what was your initial treatment approach and how did it work for you? • Did you ever consider or discuss different immunotherapy combinations with your care team? Link: https://www.emjreviews.com/allergy-immunology/news/immunotherapy-combo-shows-promise-in-lung-cancer/

European Medical Journal

Immunotherapy Combo Shows Promise in Lung Cancer

Discover a study examining whether a six-month immunotherapy regimen can improve outcomes for stage III non-small-cell lung cancer patients.