Has switching from Letrozole to Anastrozole reduced your side effects?

I have been on both, same side effects for me.

I have been on Anastrozole for 13 years now and tolerate it well. Praying for a new oncologist that understands that ER+ Herc2- MBC is sustainable for no evidence of disease.

I'm anastrozole and get hot 🔥 flashes about 2 × per day.

Changed from Anastrozole after 18 months due to hot flashes, joint pain, and other issues. Changed to Letrozole and remained on it for 2 1/2 years. Got clearance from my oncologist to stop 1 year before the full 5-year was finished due to joint pain. After 6 months, the joint pain has improved. Now I am on meds for high blood pressure and cholesterol issues (which I feel the meds intro red to). Anyone develop these issues during treatment? I would like to come off the medications - anyone have advice?

I only had Anastrozole. No side effects. Finally off it this year.

I just started taking a supplement , Chasteberry called Hormone Balance Gummies, it's really helped reduce the hot flashes.

I did both also, but the side effects from Anastrozole were also too much. I gave up the advice of all medication and chose quality over quantity. I want to live my life as if I don’t have this dire blackness over my head and not being able to interact and live. If we are like-minded people keep in touch.

Many patients in this community have experience switching between different aromatase inhibitors to find the one that works best for them with fewer side effects. Each person's response to these medications can be quite different, so what works well for one patient may vary for another - it's really helpful when community members share their experiences to help others navigate these treatment decisions with their healthcare teams.

I have been on both as well.. Anastrozole 1st. Until I looked in the mirror one day and it looked like i was getting a mustache and I pulled a big ol dark brown hair from my chin. Not happening. So I asked to be switched to letrizole but have been hesitant on taking it. I have 2 mild compression fractures in my back at L1 and L4 but they have been there a while so they are ok. Nothing to worry about I was told. I also have moderate spondylosis in my spine. So with that said, and from what I understand , both are hard on ya bones. Is that correct ?? I feel the same as someone mentioned earlier. They have messed me up with surgeries and misdiagnosis. I was stage IIIC Invasive Lobular Carcinoma lymphovascular invasions extradonal extensions macrometastis 13/20 nodes positive. Post surgical pathology report. Did 3 rounds of dose dense A/C, gained 30 lbs in 3 weeks, i figured something wasnt right, i didnt go back for anymore chemo. Never did any radiation.and just this past year i found out that , at that time, my left ventricle enlarged and my right atrium was reducing in size. Had I continued, they would of killed me. So i figured either way i could die. That was Jan 2024. In October 2024, I was told I was cancer free. I only took that Anastrozole for a couple of months. To me things just are not adding up. So please forgive me in advance. I may post and share alot. I am desperately trying to make sense of it all. Has anyone out there experienced any of these things or known anyone that has? And my thoughts and prayers out ro everyone . So many people diagnosed with some form of cancer these days. And to hear all your stories some that have been through this 2,3 & 4 times is just beyond crazy... 💯❤️