What's Next After Keytruda Side Effects for TNBC Treatment?

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MM

Community Member

2 years ago

I have TNBC and it came back in my liver 1.9 cm lesion in the RUQ. I am on carboplatin and gemzar with monthly Keytruda. The Keytruda elevated my live enzyme ALT to > 700 so we stopped Keytruda and started Dexamethasone 60mg x 1 week and then taper off. Once my liver function returns to normal will I do more Keytruda or some other biological??? What’s next????

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Accepted Answer

This sounds like a challenging situation with the liver enzyme elevation requiring careful monitoring by your medical team. Treatment decisions after immunotherapy side effects like this are highly individualized and depend on many factors including how your liver function recovers and your overall treatment response. Your oncologist will be the best person to discuss whether resuming Keytruda or exploring alternative immunotherapy options makes sense for your specific case once your levels normalize. Many others in this community have navigated similar treatment adjustments and may share their experiences here.

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HL

Community Member

6 months ago

I’m at this point too. I had to stop treatments twice because of elevated liver enzymes. I am looking into integrative therapy hyperbaric therapy and it’s this whole supplements and diet that is supposed to lessen the effects of chemo and build your body back up. Just chemo is so rough on the body. I have three young children to take care of I need more options.

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JS

Community Member

6 months ago

I had 5 rounds of Keytruda when I was doing Taxcil abd Carboplatin. Had to stop it because my creatinine levels went up to 4.4.

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CA

Community Member

2 months ago

This sounds like a challenging situation with the liver enzyme elevation requiring careful monitoring by your medical team. Treatment decisions after immunotherapy side effects like this are highly individualized and depend on many factors including how your liver function recovers and your overall treatment response. Your oncologist will be the best person to discuss whether resuming Keytruda or exploring alternative immunotherapy options makes sense for your specific case once your levels normalize. Many others in this community have navigated similar treatment adjustments and may share their experiences here.

What's Next After Keytruda Side Effects for TNBC Treatment?

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