Anyone else taking olaparib for triple negative BRCA2 metastatic cancer?

Finding others with the same specific diagnosis and treatment combination can feel isolating, especially when dealing with a newer application of a medication. Connecting with others who share similar experiences often provides valuable insights and support, so hopefully some community members will share their experiences with olaparib for triple negative BRCA2 metastatic breast cancer.

I have been taking it for over a year with no evidence of disease

Gosh, I’m glad to hear that. How are the side effects?

I was tired and nauseous for the first couple of months but taking zofran helped and continues to help today if needed. I did not have an appetite at the beginning so I did lose weight. I hope your journey is as positive as mine has been

You’re a ray of sunshine, Theresa. My appetite is fine—craving sugar mostly. I assume that’s the fatigue talking. And I sleep a lot. Sending loads of positive energy.

I am glad to be of help. Best of luck

I am triple negative with PALB2 mutation. I started on Olaparib in Aug 2025. The results have been really positive. It seems to be regressing my cancer, which is in my bones and liver. I did have side effects for the first few months of severe gastrointestinal challenges. That has all gone away and my main side effect now is fatigue. I hope you have a positive journey.

Thank you, Pat! That really gives me hope. I’ve only been on it for two weeks but my blood stats are already a little better and the pain is resolving. I’m afraid to get too pumped up (and too tired!) but hope is a wonderful thing. Sending lots of it to you.