CMML progressed to AML - what treatment options should I expect?

This transition can feel overwhelming, but connecting with an AML specialist is an important step toward getting the most targeted care possible. Many treatment combinations are available for AML that has progressed from CMML, and oncologists who specialize in these blood cancers will be able to discuss which options might work best based on specific factors. The appointment on Monday should provide clearer guidance on the treatment plan ahead, and this community is here to support you through whatever comes next.

So, basically appointment with specialist was grim. Because of my mutations, VIDAZA along with Venetoclax will not be strong enough. I’ll need a more aggressive chemo which will require 10 days in hospital and I may encounter fever and need antibiotics. Prognosis is poor

I am an AML patient since 2020 and my recent chemo was in January this year. Will you be open to alternative medicine. I am on it for 3 months now and my blood is showing great numbers.

What alternative medicine are you taking. I do see a natural pathic oncologist

I believe that’s the way to go.

I have been taking them for the past 4 months and run blood test every month. My blood reading are doing very well and hemoglobin is highest it has been. I don’t know the content or the chemical name of the herbs I am having but they came in form of capsules and a powder substance that I take twice a day mixed with olive oil.

I take Berberine, green tea, milk thistle and turmeric in capsules. I drink Essiac tea & take wheat grass shots. In addition, I take vit B, C, D & K

Hi! I'm glad you've found approaches that you feel good about. It's just worth remembering that supplements aren't risk-free or appropriate for everyone. Some can interact with cancer treatments, and certain antioxidants and herbal products have even been shown to reduce the effectiveness of chemotherapy in some situations. It's always a good idea to review any supplements/herbs with your oncology team before adding them. 💛 Suzanne (Community Moderator)

I did discuss them with oncologist

I wish the moderator and cancer doctors in general weren't so negative about taking supplements which are basically food instead of only deciding which toxic substance will best kill the cancer.

Hi David! I completely understand. Most people dealing with cancer want to do everything they can to support their health during and after treatment and nutrition absolutely please an important role in overall well-being. The challenge is that “supplements” and “food” are not the same thing. Many supplements contain compounds that can affect how medications work, including some cancer treatments. Some have been shown to be safe while others have been shown to reduce treatment, effectiveness or increase side effects. Most hematologist and oncologist aren’t opposed to supplements because they’re “natural “. They are cautious because their first responsibility is to recommend treatments that have been shown in well designed clinical trials to improve survival or quality of life while also avoiding therapies that could unintentionally cause harm. If anyone here is considering a specific supplement, we just encourage discussing it with your oncology team. There are certainly situations where supplements are recommended such as correcting a documented deficiency, but those decisions are best made on your individual diagnosis, treatment and other individualized details. This community welcomes respectful discussion about complementary approaches, but we also want to make sure our recommendations are grounded in the best available current evidence so everyone can make informed decisions. I am really glad you are a part of our community. 💛 Suzanne (Community Moderator)