CDK4/6 inhibitors with hormone therapy for HR+ metastatic breast cancer?

Thank you for sharing your experience and reaching out to connect with others in the community. CDK4/6 inhibitors combined with hormone therapy have become an important treatment option for HR-positive, HER2-negative metastatic breast cancer, and many community members have valuable insights to share about their day-to-day experiences with these combinations. Connecting with others who understand this journey can provide helpful perspectives as you and your oncologist consider future treatment options together.

Hi, I’m on Ibrance, Fasledex and Xgevia. Ive been on them for over 2.5 years. Fatigue, nausea, constipation, extremely dry skin. It’s been going good but I think I might be starting a different treatment because my labs are real low, sometimes I have to stop the Ibrance for a week or two for my blood builds back up. They have lowered my dose as well. When I get the Fasledex and Xgevia I have a couple days of bone pain and irritability. Oh my hair has thinned out but it’s coming back a little. I know it’s nothing but I think that is the worst. When I first got diagnosed it was stage2 invasive lobular breast cancer. I had bilateral mastectomy then I was on Aromisin for 8 years. Then 5 years later it metastasis to spine, most of my bones, my appendix, my stomach, my omentum. I’m worried about my liver and kidneys. I had 12 years in between. I’ll keep you in my prayers. Stay strong. Keep the faith.🙏🏼🙏🏼💗💗