Low grade endometrial sarcoma recurrence after 20 years?

Late recurrences of low-grade endometrial stromal sarcoma can unfortunately happen, and it sounds like your medical team is being proactive in adjusting your treatment plan based on current findings. Switching between different hormonal therapies like letrozole and fulvestrant is a common approach when managing this type of cancer, as doctors work to find the most effective option for each situation. Many others in this community have experience navigating treatment changes and may be able to share their perspectives on managing recurrent endometrial sarcoma.