Multiple Myeloma Progression and Recurrence

Learn the early signs of multiple myeloma relapse, including biochemical-only changes. Stay informed on symptoms and monitoring strategies for 2026.

When multiple myeloma comes back after treatment or stops responding to treatment, your care team may recommend a different combination of medicines. Findings from a phase 3 clinical trial show promising results for a combination that includes iberdomide, a newer type of treatment for multiple myeloma. The results found that people with relapsed or refractory […]

Facing a multiple myeloma relapse? Learn how to identify progression, understand M-protein spikes, and explore effective second-line treatment options today.

Learn to identify early signs of multiple myeloma relapse. Discover the difference between biochemical and clinical relapse to ensure timely, personalized care.

Every year, the American Society of Clinical Oncology (ASCO) Annual Meeting brings together cancer researchers, oncologists, and advocates to discuss the latest advances in cancer care. Some studies presented at ASCO may eventually change how multiple myeloma is treated. Others help answer important questions patients have been asking for years. Here are the multiple myeloma […]

Part of your multiple myeloma care is monitoring for treatment resistance or the cancer returning. Relapsed or refractory multiple myeloma means that the cancer has come back after responding to prior treatment. Every patient’s situation is different, which is why treatment decisions are highly individualized. Your care team will consider: How long your previous treatment […]

For people living with multiple myeloma, treatment options have expanded dramatically over the past decade. One of the most exciting advances has been the development of CAR T-cell therapy, a treatment that uses a patient’s own immune system to fight cancer. One clinical trial in particular, called CARTITUDE-1, has generated great hope for patients with […]

Multiple myeloma is often treated with combinations of therapies, including targeted drugs, chemotherapy, stem cell transplant, and immunotherapy. Treating multiple myeloma will look different based on the individual because the disease can return or become resistant, which is why researchers are constantly looking for better approaches. Clinical trials serve as a foundation for advancing more […]