Metastatic Colorectal Cancer Clinical Trials

For people with colorectal cancer that has spread to the liver, surgery can sometimes remove all visible cancer. But even after a successful operation, there’s still a chance that microscopic cancer cells remain in the body and could cause the cancer to return. A new study published in JAMA Oncology suggests that a simple blood […]

A diagnosis of metastatic colorectal cancer (mCRC) means the disease has spread beyond the colon or rectum to other parts of the body, most often the liver or lungs. Standard treatments, including chemotherapy, targeted therapy, immunotherapy, and sometimes surgery, remain the backbone of care. But for many patients, a clinical trial opens the door to […]

A new study is offering encouraging news for people living with BRAF V600E-mutant metastatic colorectal cancer (mCRC), a subtype of colorectal cancer (CRC) that can be especially difficult to treat. Results from the phase III BREAKWATER clinical trial found that a targeted treatment combination using encorafenib (Braftovi), cetuximab (Erbitux), and chemotherapy significantly improved progression-free survival […]

A recent clinical trial is offering hope for people living with a specific type of metastatic colorectal cancer (mCRC). Researchers found that combining immunotherapy with chemotherapy and targeted therapy may help patients live longer without their cancer growing or spreading compared to immunotherapy alone. The findings come from the phase III COMMIT trial, which was […]